ID   NSS_SFSV                Reviewed;         267 AA.
AC   P12792;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Non-structural protein NS-S;
GN   Name=NSS;
OS   Sandfly fever sicilian virus (SFS).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Ellioviricetes; Bunyavirales; Phenuiviridae; Phlebovirus;
OC   Sicilian phlebovirus.
OX   NCBI_TaxID=28292;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=29031; Phlebotomus papatasi (Sandfly).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2705301; DOI=10.1016/0042-6822(89)90159-1;
RA   Marriott A.C., Ward V.K., Nuttall P.A.;
RT   "The S RNA segment of Sandfly Fever Sicilian virus: evidence for an
RT   ambisense genome.";
RL   Virology 169:341-345(1989).
CC   -!- SIMILARITY: Belongs to the phlebovirus NS-S protein family.
CC       {ECO:0000305}.
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DR   EMBL; J04418; AAA47459.1; -; Genomic_RNA.
DR   PIR; B30180; MNVUSS.
DR   PDB; 7F64; EM; 2.42 A; K/L=7-267.
DR   PDB; 7F66; EM; 2.76 A; K/L=7-267.
DR   PDB; 7F67; EM; 3.59 A; K/L=7-267.
DR   PDB; 7RLO; EM; 2.60 A; K/L=7-267.
DR   PDB; 7VLK; EM; 2.27 A; K/L=7-267.
DR   PDBsum; 7F64; -.
DR   PDBsum; 7F66; -.
DR   PDBsum; 7F67; -.
DR   PDBsum; 7RLO; -.
DR   PDBsum; 7VLK; -.
DR   SMR; P12792; -.
DR   IntAct; P12792; 50.
DR   InterPro; IPR039434; NSs-like.
DR   InterPro; IPR024376; RVFV_non-structural.
DR   Pfam; PF11073; NSs; 1.
DR   PIRSF; PIRSF003956; NS-S_PhleboV; 1.
PE   1: Evidence at protein level;
KW   3D-structure.
FT   CHAIN           1..267
FT                   /note="Non-structural protein NS-S"
FT                   /id="PRO_0000221980"
FT   HELIX           8..10
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          11..19
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          22..24
FT                   /evidence="ECO:0007829|PDB:7RLO"
FT   STRAND          25..28
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          30..39
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          44..47
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          50..53
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          55..60
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          65..67
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           68..71
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   TURN            72..74
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          75..79
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          84..86
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           97..102
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   TURN            103..105
FT                   /evidence="ECO:0007829|PDB:7RLO"
FT   HELIX           108..112
FT                   /evidence="ECO:0007829|PDB:7RLO"
FT   TURN            113..115
FT                   /evidence="ECO:0007829|PDB:7RLO"
FT   HELIX           118..124
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   TURN            125..127
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           133..138
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          145..148
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           149..159
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          162..164
FT                   /evidence="ECO:0007829|PDB:7RLO"
FT   HELIX           165..182
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           187..189
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   STRAND          192..194
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           195..209
FT                   /evidence="ECO:0007829|PDB:7VLK"
FT   HELIX           211..213
FT                   /evidence="ECO:0007829|PDB:7RLO"
FT   HELIX           224..229
FT                   /evidence="ECO:0007829|PDB:7RLO"
SQ   SEQUENCE   267 AA;  30379 MW;  6C0B562F1A38EFCE CRC64;
     MINNNMMNSQ YMFDYPAINI DVRCHRLLSS VSYVAYNKFH THDVSTYEHC EIPLEKLRLG
     FGRRNSLADF YSLGELPASW GPACYFSSVK PMMYTFQGMA SDLSRFDLTS FSRKGLPNVL
     KALSWPLGIP DCEIFSICSD RFVRGLQTRD QLMSYILRMG DSHSLDECIV QAHKKILQEA
     RRLGLSDEHY NGYDLFREIG SLVCLRLINA EPFDTASSGE ALDVRTVIRS YRASDPSTGL
     TEYGNSLWTP IHSHVDENDE SSSDSDF