NST1_ASPCL
ID NST1_ASPCL Reviewed; 1126 AA.
AC A1CKE0;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Stress response protein nst1;
GN Name=nst1; ORFNames=ACLA_038250;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR EMBL; DS027056; EAW09614.1; -; Genomic_DNA.
DR RefSeq; XP_001271040.1; XM_001271039.1.
DR AlphaFoldDB; A1CKE0; -.
DR SMR; A1CKE0; -.
DR STRING; 5057.CADACLAP00003689; -.
DR EnsemblFungi; EAW09614; EAW09614; ACLA_038250.
DR GeneID; 4702898; -.
DR KEGG; act:ACLA_038250; -.
DR VEuPathDB; FungiDB:ACLA_038250; -.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_002935_0_0_1; -.
DR OMA; MLDICDT; -.
DR OrthoDB; 1374605at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR025279; NST1.
DR Pfam; PF13945; NST1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..1126
FT /note="Stress response protein nst1"
FT /id="PRO_0000324439"
FT REGION 1..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 939..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1075..1126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 479..655
FT /evidence="ECO:0000255"
FT COMPBIAS 1..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..344
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..449
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..652
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..736
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1126 AA; 125060 MW; B36972411AE61B60 CRC64;
MSTAAPAASA TNSAIPAQKE FSLPPSTDTV SVPVNRKKQK RRQKQAARLA AERQSNGHIS
PDAATQNGSS PAADPEGYHS DEFGDVDQEQ LSNGDANHKD DQDSVDAHDD YQYPGNGSEG
LQKPTGRKSK KKKGKKGPNG THAPEDETAT HASTPSVSMS HPLPPTLPSH LGPRPILKPA
KTRSIWNTST QEERENIKTF WLELGEEERR QLVKVEKDAV LKKMKEQQRH SCSCTVCGRK
RTAIEEELEV LYDAYYEELE QYANHNQGSF EKGPPIVPPP RLYQPPLRSP GQHTRTQGQF
HPSRGRIHEV PEEEDDDDLE EDYDEDEEDD EPYSDEDSDD EDDEARAARA DFFAFGNSLT
VKDGILTVAD DLLKNDGKHF IDMMEQLAER RMQREEDTQY GIAAAHQSLH SGHNHGPFDE
EDYDEEEDED YDSQEDEDYE EDEMDTMTEE QRMEEGRRMF QIFAARMFEQ RVLTAYREKV
AEQRQQKLIE ELLEEETRNE QRNAKKAREA QKRKDKKKLQ KQAKEEERAR REAEKAAEEA
AAKAEQEKKL EEQRKKREEQ RKKKEADRKA QEEERARKEA EKLRRQREER ERQAEVERKQ
REEKKRREEA RRKEKEEREL REKKAKEEQL QKDAAKAEEA AKEREKREYQ AKRTSPFSSN
QHPQISSSPV AHSPHIQSGI PVVPKAPTPA RPRQPSQQDS HTSSPHSQPA STDPSQASVS
PRSMPISQSS GASSVASKHV HGLHAMFHQP QPSAPLSPLG RSIPPGFSAM NGLPPGPPGL
TGILGRPPMA HELPVYPPHS GPFIGQFRGY PTPNGIPAAP GINGARAMPP GRGFPLESAH
GFPFHGQQQI PGAFSAQQSG LPHGHSRQPS GSFERSPLEG QTQPMPISRP SPIKRPSSTQ
QDQRKNGDRT AQRDVDDLSA HLGSSALLDD TDVPFASTLS QSLPGATAPG PLPGPARASF
GGPSLFPDPL STSGWSNNAF GSGVHHRAHT SRPVAIRLLV IQACKQLNTM SPFKGADGFH
DVSLVLRQVE QLRPQNEPSI SLKEMLDICD TEGSTQNGGG SFSTKKDETG EFVKFEPDNN
SAASGHRGSI VPGEIGSPVP SSSLPAFGGI GTPSVLRQFS SPPMGF
