NST1_ASPFU
ID NST1_ASPFU Reviewed; 1153 AA.
AC Q4WXQ7;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Stress response protein nst1;
GN Name=nst1; ORFNames=AFUA_3G10350;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR EMBL; AAHF01000002; EAL92546.1; -; Genomic_DNA.
DR RefSeq; XP_754584.1; XM_749491.1.
DR AlphaFoldDB; Q4WXQ7; -.
DR SMR; Q4WXQ7; -.
DR STRING; 746128.CADAFUBP00003799; -.
DR EnsemblFungi; EAL92546; EAL92546; AFUA_3G10350.
DR GeneID; 3511935; -.
DR KEGG; afm:AFUA_3G10350; -.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_002935_0_0_1; -.
DR InParanoid; Q4WXQ7; -.
DR OMA; MLDICDT; -.
DR OrthoDB; 1374605at2759; -.
DR Proteomes; UP000002530; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR025279; NST1.
DR Pfam; PF13945; NST1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..1153
FT /note="Stress response protein nst1"
FT /id="PRO_0000324440"
FT REGION 1..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 447..658
FT /evidence="ECO:0000255"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..363
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..463
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..862
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1153 AA; 127978 MW; 9FC87AE64C896523 CRC64;
MVPAPHTQHY SSSTMPNSSS TTAHSAPTTN GDVHAPKDHQ LSSPSDTVPA PVNRKKQKRR
QKQAARLAER QLANGHVSTD DATQNGSSHT NPERHHSDDG GADGPDHEQP ANGDVYPKDG
QDSTEAHIDS QNPQGPNGTE SSQKSTGRKS KKKKGKKGRN GSHAQGDETS TPMSTPSVSM
SHPLPPPLSS HLASHNILKP AKNRSIWNTS TQEERENIKT FWLELGEEER RQLVKVEKDA
VLKKMKEQQR HSCSCTVCGR KRTAIEEELE VLYDAYYEEL EQYANHNQGS FEKGSPMVPP
PRLYQPPLRS PGQHTRTQGQ FHPSRGRIHE LTEDDDLEEN YDEEEDDGDE PYSDEELDEE
DEETRAARAD FFAFGNSLTV KVADDLLKND GKHFIDMMEQ LAERRMQREE DTQYGIAAAH
ESLHSGHNHG PFDDEDYDDE EDEDYDSQEE EDYEEDEMDA MTEEQRMEEG RRMFQIFAAR
MFEQRVLTAY REKVAEQRQQ KLIEELMEEE TRNEQRNAKK AREAQKRKDK KRLQKQAKEE
ERARREAEKA AEEAAAKAEQ EKKLEEQRKK REEQRKKKEA ERKAQEEERA RKEAEKLRRQ
REERERQAEA ERKQREEKKR REEARRKEKE ERELREKKAK EERDRKAQEQ QAKKDTAKGG
EEAKDQEKRD DQAKRSSQQV PVPIPTNLHH LQGLSPTVAH SPHVPSATPV LPKAPTPAKP
RQPSQQDSHS SSPHSQAPST DPSQASLSPR SMPVSQSSGV ASGNSQQGQG LHAMLHQPQP
STPLSPLGRS IPPGFSSVNG IPPNPPGLSG MVARPPVGHD LPSYPSHSGP FISPFRGYPA
PTGIPAPPGI NGARPMPPGR GFPLEPAQGF AFHGQQIPGA FSTPQGGLPH RHSRQPSGSL
ERSPLENHAQ PMPISRPSPI KRPSSTQQDQ QKGDDRTTQR DVDDLSAHLG SSALLDDSDV
SLSSNLSQSL PGATVPGTFS GPARASFGGP SLFPDPLSAS GWSNNAFGSG GHHRAHTSRP
VAIRLLVIQA CKQLNTMSPS KGADGYHDVN LVLRHVEQLR PQNEPSISLK EMLDICDTEG
NTQNGGGTFS IRKDETGEFV KFEPDNNSAA SGHRGSIVPG EIGSPVPSSS LPAFGGIGTP
SVLRQYSSPP MGF
