ID   NST1_CANGA              Reviewed;        1320 AA.
AC   Q6FM98;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Stress response protein NST1;
GN   Name=NST1; OrderedLocusNames=CAGL0K09834g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR   EMBL; CR380957; CAG61609.1; -; Genomic_DNA.
DR   RefSeq; XP_448646.1; XM_448646.1.
DR   AlphaFoldDB; Q6FM98; -.
DR   SMR; Q6FM98; -.
DR   STRING; 5478.XP_448646.1; -.
DR   PRIDE; Q6FM98; -.
DR   EnsemblFungi; CAG61609; CAG61609; CAGL0K09834g.
DR   GeneID; 2890202; -.
DR   KEGG; cgr:CAGL0K09834g; -.
DR   CGD; CAL0134577; CAGL0K09834g.
DR   VEuPathDB; FungiDB:CAGL0K09834g; -.
DR   eggNOG; ENOG502QSSK; Eukaryota.
DR   HOGENOM; CLU_267374_0_0_1; -.
DR   InParanoid; Q6FM98; -.
DR   OMA; TLDSHWE; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009651; P:response to salt stress; IEA:EnsemblFungi.
DR   InterPro; IPR025279; NST1.
DR   Pfam; PF13945; NST1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT   CHAIN           1..1320
FT                   /note="Stress response protein NST1"
FT                   /id="PRO_0000324445"
FT   REGION          1..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          541..598
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          656..766
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1048..1073
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          637..807
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..18
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..82
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..592
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1320 AA;  150796 MW;  381FE102C2A5047C CRC64;
     MPSGSKSKKK KSKSKGGVKK HAVEKVAPPI EAEIMDERDE SDYPTSRVIK RGPNGDVIVE
     SLPDKSTSGK KSKKKGKLSD LEVSESAKQM GITLDSHWES LSPDEKKNIL RIEKEEVLEI
     IRNYQNDHNC SCSVCGRRHM AMNQEMERMY NLLYELEEQR DPDMNPVKFH LGIIKELQIS
     KNKQILDQTE GPNDNTTHEE VVKNFLSSDI ADKLKEEVHQ FKQKQLSKQE CNRPSSLAND
     NIEEEIPCAQ IPQANEEAMT KDIQKTLEQL SVVEPVSKIN VIQEDDLGEI KEENKEYLKF
     TESFISSQPK IAQKFIQKLD ENPCMKAITD EVMQNSSYEF LDALKNLWAP NLLKIVESED
     DDNLVNLNET LDPIEFTTML HHGNPLSQQD YYDLQGAISR KVVNAFNFEN RKLEHLSPLE
     VELFGRFMSS DQDNIFHNML LEAYNERFKE EPFKMMSNIP QIIKAVATLT NLDGRMMDDV
     DENHFTSEEE RYDDDITDYS DSEYEDYDSE YDDIDNGDII SDVDEPFSTL KSDQLRVNYD
     TNSGNINHSD NYESNSRLRE VTDENEENLQ YDTPQEKYNY SDHGKDHGTI ADEDEDSIDE
     GYESSIDDME RLEEGRRLIQ IAITKLLQGR IMESYHEKEA DSNRLKLLKE LEEEQMKKKE
     KEVKKIKKKE KEKEKRRLQQ LAKEEEKRKK EEEERSAREE QERREMERRE AQRKKVEEAK
     RKKDEERRRK LEEQRKREEQ QEKQRKAKEE QKRKREEEKK KKEELERQLR EEELMKKKEE
     EERLLREKER AEILKKETEL AMSMKENHSS QSLSIQNQFF SNPQNSNIGM QNYFNNDLDN
     TNAGLGNGGP TNLGVRKNSH VLGLTQVYSD KANNSPGKND DNNEINNEIL NIINAATTAK
     SGSRTSMDMQ ALLQPPFTDN VNDQIRSSNL INDQASGMNS NGLSTNFHSP YGSNVFSGEN
     QLSNNLQNDI LTGLNADTSS TNLASWTSLP ALNNLNANQH ILSNNQTPLH QQKGTSPISN
     TMMDTKRDYL GDELSKLTTM LTTNSLNESP AFSSSNLQSS LWNDQNSSGK TPLGSNTTQI
     PLSQPAFLGT EPPVHRSSIW GDSSASMFNF SQRLSVPTNS NSVSSQTVPN QNIGMGSSFT
     NPSIWSTGSD FNVPSRDMNS GVAFTNSFSN TSPRNQFALN SGSMLQNQSQ RQNIMDNIRL
     LSNSPQNNGY IPIDLLYQSI NKQSTSDFPS FLNNVIDLER SHNYDLVKDQ TGVINGVRVG
     SENRPVSTAF SNFHQNMDPT MKGPEHLSNS IPGTARNFEG NSYLAKEATM NIIPSSSLDR