NST1_DEBHA
ID NST1_DEBHA Reviewed; 1179 AA.
AC Q6BUT3; B5RT89;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Stress response protein NST1;
GN Name=NST1; OrderedLocusNames=DEHA2C08206g;
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR EMBL; CR382135; CAR65551.1; -; Genomic_DNA.
DR RefSeq; XP_002770186.1; XM_002770140.1.
DR AlphaFoldDB; Q6BUT3; -.
DR SMR; Q6BUT3; -.
DR STRING; 4959.XP_002770186.1; -.
DR EnsemblFungi; CAR65551; CAR65551; DEHA2C08206g.
DR GeneID; 8998337; -.
DR KEGG; dha:DEHA2C08206g; -.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_003284_0_0_1; -.
DR InParanoid; Q6BUT3; -.
DR OMA; HEVRDIN; -.
DR OrthoDB; 1180340at2759; -.
DR Proteomes; UP000000599; Chromosome C.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR025279; NST1.
DR Pfam; PF13945; NST1; 2.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..1179
FT /note="Stress response protein NST1"
FT /id="PRO_0000324449"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 957..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 648..810
FT /evidence="ECO:0000255"
FT COMPBIAS 21..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..616
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1179 AA; 133686 MW; 00DC884F2BC38E81 CRC64;
MSETQSDPID VSKFKNGDDV HFDYNSTTND QTINSTNVQK KKKKKKSKNK HKGSPNVEAT
LNDPDVEYPT SRVIKQAPNG DVIIESLDEP SDAHTKSVTA NIWDNATLEE QENLKAFWES
LDEAQKIELV KIDKKSIMDI FKNESKTVNT SNNHQNNSNT QGGSTSTSGG ALNGSSTNVN
IPGAPSNSSN GACTCSYCGR KNNFIEDELE NIYDNHFDDI IDFIHEVRDI NDLNALPGLL
FGGFHMLEEE HKLQKRQQKY KYKQERDAHH DHHNHEPGHI CSDTGSSGDY DGSTQQDQQH
QYEHEIEHAF QEDEHEDECG HKNDHSHSHS HSHTENHNHS HSYDPNHNHS HSHFQYDQIE
ELNNEDELSQ EAVLQKSLDD ELNKELGDES NNNQSSIATK EQRVFHKLLD PKLFEALENL
DFEKMKDTPA NNHSAHILEK AGSLRDIIRD LHKADKVELE KGMAFLQNMG KIFSSDMSNA
MNHDTLNDQI SNGLSSFAED LLKNDGNSFI DMMESLSESR TAREDLLKEK FDKEPSAAWI
DEDDHTKSDT DISIPKPDLH QVQELEEELN DEYDEVDEDD DEGEEEGEEE EEELDDEEFE
EDEEEDASDT ESEISEEEKM QEIRRLFLIQ VIKLFQERLK NAYKEKLSQD RTRTLIEELE
AEENAKKERE MKKLRQKEKA KEKKRLQQLA KEEERRKKEE EQKAKEEELK QKQEALRAEQ
RRKKEEAKQK REEEKRKRIE ELKRKELEHQ KRLEAQRKKE EETKKLKDEK KKKIEEERKQ
KEEEKRQKEL QKKLVEEERS KSAKKQDHKE TGSSEDISQL SRDLENARLG QNFNIPSPVV
PDTLLAQPQE PRVKSPTKNH ILDQLYLAKP RSLSNSTNST PQINNVTPGY IPDLSSNSML
PSVLSPSGHN ILPNNGNVNN QAVPSPWSSQ AFNANTQAPP VYQPQLSSNA FSPFNSSLSQ
NSLSSNANEN LNTNPLNTTG FNEPFATAAQ PSSVWNPGAT SRNNSIWSNS PNVASNSTLW
GNSVPAPPVG AAVGGNPNSL DSDLIQAAAY QAFQFLQNSN QLEFGVAPSL KLFQTAKTIL
SNQGLTLNQF LTSCRNTGSL SGYGFDFIYD DFGTVTHIKA SSTNIPQQPP HNNVNTQSIN
SLGLGNAAVN DNESSLLNTL SDINNNPNSF SNGVRGLWN
