NST1_EMENI
ID NST1_EMENI Reviewed; 1125 AA.
AC Q5B3C8; C8V920;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Stress response protein nst1;
GN Name=nst1; ORFNames=AN4952;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR EMBL; AACD01000084; EAA61030.1; -; Genomic_DNA.
DR EMBL; BN001303; CBF76408.1; -; Genomic_DNA.
DR RefSeq; XP_662556.1; XM_657464.1.
DR AlphaFoldDB; Q5B3C8; -.
DR SMR; Q5B3C8; -.
DR STRING; 162425.CADANIAP00005444; -.
DR EnsemblFungi; CBF76408; CBF76408; ANIA_04952.
DR EnsemblFungi; EAA61030; EAA61030; AN4952.2.
DR GeneID; 2872751; -.
DR KEGG; ani:AN4952.2; -.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_002935_0_0_1; -.
DR InParanoid; Q5B3C8; -.
DR OMA; MLDICDT; -.
DR OrthoDB; 1374605at2759; -.
DR Proteomes; UP000000560; Chromosome III.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR025279; NST1.
DR Pfam; PF13945; NST1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..1125
FT /note="Stress response protein nst1"
FT /id="PRO_0000324450"
FT REGION 1..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 415..636
FT /evidence="ECO:0000255"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..332
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..431
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..635
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..658
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 735..760
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 883..907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1125 AA; 124576 MW; 7359CC208ED17EEC CRC64;
MSSHVPAVTA PTPSTVSENS ASKDSHSSPM PESKPVSVNR KKQKRREKAA RLAAQRQAAN
GHAPSDTLDV NGSSSTVLDN DVSHEQSGGG YDDKSEKVLN GHGHNTQELP HPSEHDPQGT
TSRKSKKKRG KKGRNGSQAS STPMSTPSIS LSNAPRPPLS SHFGSQSSSK LLKERSIWNT
STQEERENIK TFWLELGEEE RRQLVKVEKD AVLKKMKEQQ KHSCSCTVCG RKRTAIEEEL
EVLYDAYYDE LEQYANNTQG SFERGPAILP PPGLYQPPLR SPGQHTHTHG QFHPSRGRIH
EPEDDEDLEE DYDEDEEDDE PYSDEEYEDD EGSAARADFF AFGNSLTVKV ADDLLKNDGK
HFIDMMEQLA ERRMQREEDT QYGIAAAHQS LHSSHNHGPL DDEDYDDEED EDYDSQEEEE
YEEDEMDAMT EEQRMEEGRR MFQIFAARMF EQRVLTAYRE KVAEQRQQKL IEELLEEENL
NEQRNAKKAR EAQKRKDKKR LAKLAKDEEK ARREAQKAAE EAAAKAEQER KLEEQRKKKE
EQRKKREAER KAQEEERARK EAEKHKRLRE ERERQEEAER RQREQKEQEK KRREEAKRKE
REERELREQK AKQERERKAQ DEQSRRERER VAQEQAKRAP NLQPVSPVSP PPESATPVVS
KAPTPAKGRR PSQQGSHSSS PRSQSASAEA SQVSPRSAPL SQSSGSSIPK YGSGHPILHP
HPGAPMSPLG RTHPPGLSPS NPPGLSGLVP RPPMGHELPT YPPHSSPYMN QLRGFPAPNG
IPVLPGMNGT RPMPPGRGFP LDAPGIPFHA QPPFSGIFSP QPSGLPHGHS RQPSNSFERS
PLDTSAQPFP ISRPSPIKRP PSTQQEQRNS RRDVDDLSAQ LGSSALLDDS DVPLTSSQLS
QSLPGTTPAP VMPGPARASF AGSSLFPDPL SVAKHANFPV SPVIGGSTWG AQMPFGAPFP
GGPTWGYTPA NNNAFGAGIH HRAHTSRPVA IRLLVIQACK QLSTMSPSKD SGGYHDVNAV
LRQVEQLRPS NEPSISLKEM LDICDTEGNA QNGGGTFSIK SGQTGELVKF EPDAVSTTTG
HRGSIVPGEI GSPIPSSTMP ALGGIGLGTP PSSALRQFSS PTTGF
