NST1_LODEL
ID NST1_LODEL Reviewed; 1637 AA.
AC A5DXA0;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=Stress response protein NST1;
GN Name=NST1; ORFNames=LELG_01987;
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC YB-4239;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR EMBL; CH981525; EDK43808.1; -; Genomic_DNA.
DR RefSeq; XP_001527158.1; XM_001527108.1.
DR AlphaFoldDB; A5DXA0; -.
DR SMR; A5DXA0; -.
DR STRING; 379508.A5DXA0; -.
DR PRIDE; A5DXA0; -.
DR EnsemblFungi; EDK43808; EDK43808; LELG_01987.
DR GeneID; 5233720; -.
DR KEGG; lel:LELG_01987; -.
DR VEuPathDB; FungiDB:LELG_01987; -.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_003284_0_0_1; -.
DR InParanoid; A5DXA0; -.
DR OMA; HEVRDIN; -.
DR OrthoDB; 1180340at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR025279; NST1.
DR Pfam; PF13945; NST1; 2.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..1637
FT /note="Stress response protein NST1"
FT /id="PRO_0000324452"
FT REGION 1..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 681..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..1036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1049..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1176..1299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1512..1534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 855..1023
FT /evidence="ECO:0000255"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 755..812
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..1020
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1065
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1176..1265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1279..1299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1637 AA; 184457 MW; F9A8425B84AD6506 CRC64;
MSNRGNLNLN LPPSSGKYTV GENVHFELSK EKNNSTNSNP HTSSTSTSNS NNTGIGVAKS
LSTNDNNNDN DNQQPQQHEQ IQSKAKSQSQ SQSQSQSQPQ TQVQVEQQQQ QQSLVNSPAA
QLAAKKRKKK KSKKSSNNNG NNSNTNSNSN SEITNTSISM PHAFLNNPDE DYPTSRVIKQ
APNGDVIVES LDHVGGTYED HLHDDYSDED TLHHHLRQAP HQASNNNHIH NHSHTSSHPL
QHTPNHLHHA SHNANPLTQH ISASGASMRS HGHNDAHSNL WDSASLEEQE KLKEFWESLE
ESQKLDLVKI DKQSIMKMFK NETRQHLQQL LQNGVLNNQN ASSSNNCACK YCGRRNNIIE
EELENIYDNH FDDIIDFIHE VRDINDLNAL PGLLFGGFHM LEEERRLQKR KQLHNEHLEL
AKSSNLQNQA HIEEIRAQMD KLKMNQRQQS QSQSQSQSQQ QRDVQTAQSQ VLSKDSSLKN
ANTSMNKQHT SQQLLQPQIQ AQGKNNLQQN HHTHHHHQQP LQHPTVQISA TFLSSNPTET
QLFNKLLDPK LFEALESLDL QKMKEVSHFD PQNTAHINML EKAGSLREIV RDLHNVDRNH
LEKGMSYVQN MGKLFSNIAS LNPSNPEDAE KIMTGQLNEQ FNQGLSTFAE DLLKNDGSSF
ISMMETLSEL RSAREELLKE KTPYNGLLTK TPAATSQDRE QQVQPNHSHW LDEDDHDHEH
EHEHEHEHEH EIDDEDHEHY CCHHHQHHHL HGDEEYDEED EEDDEEYEYG DDEEEEDEED
EEEGEDEELE EVVEDDVDEE ILDDEEEFDA KNASDTESEI SEEEKMQEIR RLFLIQVIKL
FQERLKSAYK EKVSKDNTRK LFEELEAEEA AKREKEAKKL KQKEKAKERK RLQQLAKEEE
KRKKEEEAKR IAEELHAKQE QLKLEQKKKK EEARLRREEE KKKKLEEIKR REAEHKRKVE
EQIKHDEEQR RLKEERRKEL EEKKRQKEEE KKQKELLKKQ KEEEKERLRI EREKQLEKEA
AVSKSIPQPS PKSKHVMKLA ATFQSDIPSK QNQAQNGNQS HLPPQSRLRQ DEENPQKTFA
NSVFSAKEYN SIYQPLPGSL SNNSSSAALS VGTQLSNFQA LSHPQQQQQQ YSNDIYLPSA
NLATATVQSP RSAPINLPNG TSAVGVSLAN HLSLNNSSQG SPWTTNSTLS SNLGSTGLSH
GQGQTVSGVN TNLPSSIGIT SGGASQIFQP QPQPQLQPHQ PQQQQQQQQQ QQQQQQQNYF
SPFNSFSEPL VGEPFQGIVH PTTNINNSTT ASSSTGAIIP PMNPSGNIWN SNIGATATNA
PASVSRNNSV WSNNAITPKP SEPSFLSTAG RSSSLWGTLA NAPVASSSNN NSNATANYDN
NNVRSLGSSS FAPANPGQHE LEVIQTAIYN CFQMMQNSNQ LEFNVAPLMA IFSNVRSLTN
KTQLTVNQFL NCCVSNSLYQ FDFVYDDFGT VTHLKVGLNG LNDHNSVNGF SKSSTTPPLL
PISAMNSKIL GYTQQQQQQQ QPQPQPQSQQ QYPLQHSHQQ RLLQLFSNNQ TILSQDVTSS
AFATGTNTQG SSYGQVQLGA VSPAFARTSP PGLFPNDIPL LSTINELNST PSTGTGTGTG
SGVGAGTGAV FGSGIWN
