NST1_SCHPO
ID NST1_SCHPO Reviewed; 1085 AA.
AC Q09863;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Stress response protein nst1;
GN Name=nst1; ORFNames=SPAC29E6.10c, SPAC30.14c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-883, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR EMBL; Z66525; CAA91432.1; -; Genomic_DNA.
DR EMBL; CU329670; CAB66473.1; -; Genomic_DNA.
DR PIR; T38511; S62516.
DR RefSeq; NP_594568.1; NM_001019997.2.
DR AlphaFoldDB; Q09863; -.
DR SMR; Q09863; -.
DR BioGRID; 278947; 1.
DR STRING; 4896.SPAC29E6.10c.1; -.
DR iPTMnet; Q09863; -.
DR MaxQB; Q09863; -.
DR PaxDb; Q09863; -.
DR PRIDE; Q09863; -.
DR EnsemblFungi; SPAC29E6.10c.1; SPAC29E6.10c.1:pep; SPAC29E6.10c.
DR GeneID; 2542488; -.
DR KEGG; spo:SPAC29E6.10c; -.
DR PomBase; SPAC29E6.10c; nst1.
DR VEuPathDB; FungiDB:SPAC29E6.10c; -.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_281888_0_0_1; -.
DR InParanoid; Q09863; -.
DR OMA; YANIQRN; -.
DR PRO; PR:Q09863; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR InterPro; IPR025279; NST1.
DR Pfam; PF13945; NST1; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Cytoplasm; Phosphoprotein; Reference proteome;
KW Stress response.
FT CHAIN 1..1085
FT /note="Stress response protein nst1"
FT /id="PRO_0000116425"
FT REGION 22..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 927..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 971..996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 561..744
FT /evidence="ECO:0000255"
FT COMPBIAS 508..526
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 883
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 1085 AA; 122941 MW; 041164132676F233 CRC64;
MNDKALRTEA LSVGLEPPSF KDLLIPIPNS GTKKKNKKKK KPKAKKNVET QANVDLLGSA
GTDSAVTDVG ANNGVIDHQA SLELSNLNSR ISHPQLVSAN GDDSSLINVE GISSTDWQFT
LESDDTIEHS PQCILSTSSF VDEAEFPVHI PGLEDATSSN MSPNSVQNNM NLNTVALGSS
TSSKRKKKKK KKSKANSASL NVDDQRDFEQ VYSTDVAITY RNGQALSYYN GSVRQASMNN
NVNNNKSKDI WSSSNTEERE QIREFWLSLS ESERRSLVKV EKEAVLQKMK EQQKYSCSCS
VCGRKRLAIE EELEVLYDAY YEELEQYANI QRNLANTESV NASDEGSDKS QKGIISDSPK
LLSIPLNNVP SKSLNDDITQ DELNSSNADV DEEVIETTSL EEKNVDNQEF VTSISNGNQT
LEDTSHSPQT QPPFQPPYPS KADEKNSYHS DLYNFGSSLT VKGGILTVAD DLLKNDGKKF
IEMMEQLAER RMQREDNSNF HEPELYESGL EYDEDEEEDE EDVDEDELDL MTDEQRMEEG
RRMFQIFAAR LFEQRVLQAY REKVAQQRQA KLLEEIEEEN KRKQERELKK IREKEKKRDK
KKQLKLAKEE ERQRREAERL AEQAAQKALE AKRQEEARKK REEQRLKREQ EKKQQELERQ
KREEKQKQKE REKKLKKQQQ EADREKMARE QRLREEEEKR ILEERKRREK LDKEEEERRR
RELLEKESEE KERRLREAKI AAFFAPNQTK EGSDGCTTSS QLGLFEKKGD LVNDEDKLSS
HLLDSVPNAL RQAPIGLKNT NNLSERNASS NLLNSSLFSS FNSVNPLISL EPNPLNRTLN
NSVNLTDFGR KPNGLHSPSS LLSNSNNFGL NPNARHSLSR ANSPVHHYPF ATPPSQRANK
YPLNNGANVP ALLNSFSSPQ LSPLVNRVLN EPSSSPLSSS SLKSPLSKEG VLNQQGHEQY
NFSLSPSIRN KLSPICRPSQ GSSPKLKNNL SNTEERMGSR ALLDDKTDSV ITASNSTTSG
LSRDESSNPN NYELLNAFNQ NTWKISRSTS NKSLIPESPW GVALGAFTPN ASTQSIPWGN
RTWTD
