ID   NST1_VANPO              Reviewed;        1334 AA.
AC   A7TR75;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Stress response protein NST1;
GN   Name=NST1; ORFNames=Kpol_1029p17;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: May act as a negative regulator of salt tolerance.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NST1 family. {ECO:0000305}.
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DR   EMBL; DS480471; EDO15243.1; -; Genomic_DNA.
DR   RefSeq; XP_001643101.1; XM_001643051.1.
DR   AlphaFoldDB; A7TR75; -.
DR   SMR; A7TR75; -.
DR   STRING; 36033.XP_001643101.1; -.
DR   EnsemblFungi; EDO15243; EDO15243; Kpol_1029p17.
DR   GeneID; 5543303; -.
DR   KEGG; vpo:Kpol_1029p17; -.
DR   eggNOG; KOG0516; Eukaryota.
DR   HOGENOM; CLU_267374_0_0_1; -.
DR   InParanoid; A7TR75; -.
DR   OMA; TLDSHWE; -.
DR   OrthoDB; 843405at2759; -.
DR   PhylomeDB; A7TR75; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025279; NST1.
DR   Pfam; PF13945; NST1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome; Stress response.
FT   CHAIN           1..1334
FT                   /note="Stress response protein NST1"
FT                   /id="PRO_0000324461"
FT   REGION          1..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          530..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          712..849
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          977..996
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          694..876
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..17
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        539..553
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1334 AA;  152243 MW;  0ED2B83F5EE4B26B CRC64;
     MPSHSKNKKR KSKSKGGSTV KKSGGLLEKG IGNITAELYN DTDDYPTSRV IKRAPNGDVI
     VESLPTKPKK SKSRQTNSSS NNDMILDLDS HWEWLSPEEK KNILRIDKDE VFEMLSRYNN
     HNSNNVNGNT NNNNIIGTGS NNLSGGISTN SNNNTSSSCN CNVCGRRHMA MDQEMERIYN
     RLYEMQRENY EDMTHIKFHL NIIKDLQKRK TQMISPPASP EMDSNNVDEA REPNSGSSNE
     SLDIKNDLET MRDEVVKYFL SPNSVDTLKK EVLNFKHNKQ KQFQTPISLN EDNTEEVVED
     NEAQHIYDDL SNEIHDSGLI ESPRTVEDDA NIIDIESKSR YLNFAKTFIS SHPTIAQEYV
     NKMIMYPEMK ELTDDLMNNN GSGFIKAIEE FVLDKQKQNT LPDTEIDIND VNSQQHENPE
     EALQVQDLGD AKEFTTMLHN GQPLTSDEYA NLQRHIAERV TDAYNTETKE FEGISQLEKE
     LFTRFMHGSD RRQFGDSILQ LFKNKYDDKL SANSISTSLA AAASTITHDI ISPRNDDGND
     TEEDIDYYDD EDDVSSENIH HRNDLDDDFK SREEYSDYNS DFHDNRKCEK YNDFDDDDDY
     LDNNRNLECA HAEHNHETLS TYHHDVDLAD SNSHGYKNYA SHHTSSQVSE DYIDDIDDDG
     YESGIDENER LEEGRKLLQI TITKILQRRI MESYHAKQAE NNRMKLLEEL EAEESKKKEK
     EEKKQRKREK EKEKKRLLQV AKEEERKKKE EEAERLKKEA EEREMERRET QRKKVEAAKK
     KKDEEKKRKL EEQRKREEEQ ERQRKIKEEQ KRKKDEERKQ KELEKKKKDE EKRIQEEEKR
     KKEEEAEQKT LNEKKRLDVE IMEQKRLEEE EKRLKSTAST SNVPYAELLK MTPSLQPVSG
     NINDELFGMI NAATSSQSIP TSSSHLNHLL QQNDASHFNM TPRHDLLNPS GGMHFGPSDL
     IEQSHFTHKS NSFDTLAAIN DPTTPQTTLP YGNSSVPPNS FDISSWGNFN GSSTAETQLQ
     SQLPQQSLLG SHSVTSDQNR KSFNEELNTI TNLLSTTGLE DQLSQKDSFA HSSLWGSQGT
     SLSGSNPNLS SNFAPAGLPI NQTPISPGNI GIPTTTHRSS IWDISSGVDY SLNDNKITGS
     IQSERPLSNV IPSSYMSPNI WSGGTSKIPV IEQPLVFNPN ENQTNPISNI ILRELSLLTL
     PNSTDQYVSS ELLCQKVMAN RIDYGVYFTE LMNLRNAHKI EIASNDNGQV THVKLVYKSK
     DELEMPLNSS ENQNSHIQMQ QNYGLQPISS TTAGNTASTT ANNANGSTIN TSNSHFFNIN
     KTISNPSVTA NIWS