NSTU2_ARATH
ID NSTU2_ARATH Reviewed; 398 AA.
AC Q9FG70; A0MFP6; Q8LB26;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Nucleotide-sugar uncharacterized transporter 2 {ECO:0000305};
GN OrderedLocusNames=At5g55950 {ECO:0000312|Araport:AT5G55950};
GN ORFNames=MYN21.6 {ECO:0000312|EMBL:BAB08660.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY.
RX PubMed=25053812; DOI=10.1073/pnas.1406073111;
RA Rautengarten C., Ebert B., Moreno I., Temple H., Herter T., Link B.,
RA Donas-Cofre D., Moreno A., Saez-Aguayo S., Blanco F., Mortimer J.C.,
RA Schultink A., Reiter W.D., Dupree P., Pauly M., Heazlewood J.L.,
RA Scheller H.V., Orellana A.;
RT "The Golgi localized bifunctional UDP-rhamnose/UDP-galactose transporter
RT family of Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:11563-11568(2014).
RN [8]
RP GENE FAMILY.
RX PubMed=25804536; DOI=10.1105/tpc.114.133827;
RA Ebert B., Rautengarten C., Guo X., Xiong G., Stonebloom S.,
RA Smith-Moritz A.M., Herter T., Chan L.J., Adams P.D., Petzold C.J.,
RA Pauly M., Willats W.G., Heazlewood J.L., Scheller H.V.;
RT "Identification and characterization of a Golgi-localized UDP-xylose
RT transporter family from Arabidopsis.";
RL Plant Cell 27:1218-1227(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TPT transporter family. TPT (TC 2.A.7.9)
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28760.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AB026659; BAB08660.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96702.1; -; Genomic_DNA.
DR EMBL; DQ447080; ABE66252.1; -; mRNA.
DR EMBL; DQ653372; ABK28760.1; ALT_SEQ; mRNA.
DR EMBL; AK230288; BAF02090.1; -; mRNA.
DR EMBL; AY087465; AAM65010.1; -; mRNA.
DR RefSeq; NP_200406.1; NM_124977.4.
DR AlphaFoldDB; Q9FG70; -.
DR SMR; Q9FG70; -.
DR STRING; 3702.AT5G55950.1; -.
DR PaxDb; Q9FG70; -.
DR PRIDE; Q9FG70; -.
DR EnsemblPlants; AT5G55950.1; AT5G55950.1; AT5G55950.
DR GeneID; 835693; -.
DR Gramene; AT5G55950.1; AT5G55950.1; AT5G55950.
DR KEGG; ath:AT5G55950; -.
DR Araport; AT5G55950; -.
DR TAIR; locus:2178373; AT5G55950.
DR eggNOG; KOG1441; Eukaryota.
DR HOGENOM; CLU_048347_1_1_1; -.
DR InParanoid; Q9FG70; -.
DR OMA; GVLLFQW; -.
DR OrthoDB; 938634at2759; -.
DR PhylomeDB; Q9FG70; -.
DR PRO; PR:Q9FG70; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FG70; baseline and differential.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR GO; GO:0005338; F:nucleotide-sugar transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005464; F:UDP-xylose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR004853; Sugar_P_trans_dom.
DR Pfam; PF03151; TPT; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Sugar transport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..398
FT /note="Nucleotide-sugar uncharacterized transporter 2"
FT /id="PRO_0000439528"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 299..319
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 17
FT /note="Missing (in Ref. 6; AAM65010)"
FT /evidence="ECO:0000305"
FT CONFLICT 330
FT /note="I -> V (in Ref. 6; AAM65010)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 398 AA; 42644 MW; E4E9BF3B83901268 CRC64;
MGLVDSLLGK DARKFLKRKD SDAAEAGRAL EELRSSLYNE LKTSEGAKRQ QQRFCGPVVA
MSFNFVVAVG IILANKLVMG RVGFNFPIFL TLIHYTVAWI LLAFFKSLSL LPMSPPSKTT
PFSSLFSLGA VMAFASGLAN TSLKHNSVGF YQMAKIAVTP TIVLAEFVLF KKTISSTKVM
ALAVVSLGVA IATVTDLEFN LFGALVAVAW IIPSAINKIL WSNLQQQANW TALALMWKTT
PFTVFFLLAL MPWLDPPGVL LFKWDLTNSS AILISALLGF LLQWSGALAL GATSATSHVV
LGQFKTCVIL LGGYVIFGSD PGFISICGAI AALGGMSVYT WLNLPGKSID HMSNKQLPKQ
NVTVSKPKAE ADDGGGETGV TVVSVDPLLS KTITANIV
