ID   NTCB_SYNE7              Reviewed;         309 AA.
AC   P52693; Q31NU7;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Probable nitrogen assimilation transcriptional activator;
GN   Name=ntcB; OrderedLocusNames=Synpcc7942_1242;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7814317; DOI=10.1128/jb.177.2.290-296.1995;
RA   Suzuki I., Horie N., Sugiyama T., Omata T.;
RT   "Identification and characterization of two nitrogen-regulated genes of the
RT   cyanobacterium Synechococcus sp. strain PCC7942 required for maximum
RT   efficiency of nitrogen assimilation.";
RL   J. Bacteriol. 177:290-296(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Seems to regulate utilization of fixed nitrogen by
CC       controlling the expression of a certain gene(s) involved in nitrogen
CC       metabolism.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; D16303; BAA03810.1; -; Genomic_DNA.
DR   EMBL; CP000100; ABB57272.1; -; Genomic_DNA.
DR   RefSeq; WP_011242622.1; NC_007604.1.
DR   AlphaFoldDB; P52693; -.
DR   SMR; P52693; -.
DR   STRING; 1140.Synpcc7942_1242; -.
DR   PRIDE; P52693; -.
DR   EnsemblBacteria; ABB57272; ABB57272; Synpcc7942_1242.
DR   KEGG; syf:Synpcc7942_1242; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_0_3; -.
DR   OMA; GKQPELC; -.
DR   OrthoDB; 990666at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_1242-MON; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..309
FT                   /note="Probable nitrogen assimilation transcriptional
FT                   activator"
FT                   /id="PRO_0000105725"
FT   DOMAIN          1..57
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   309 AA;  34901 MW;  AAE073F53F46139B CRC64;
     MRLEQLQAAL RVAETGSFQE AAQKVGCNQS TISRQVKGLE DELGIALFRR QGRMKLTAAG
     ERLLPRLRRI CQEWQTACTE IEELLTGRQT ELCMAIADSI GGCYLPAVLN RFQQQWPSIH
     LRVSTLGSDR ALKVLRDGLI DLAIVMDSPT LTTSAGLVVD LLLEEEVQVL LSVDHPLADQ
     KAIAWEQLSH VPQVVFKDGY GMQRLVEQRF RELGLELNSC LELNSLDSFR GVVREGYWLA
     LLPQAALVDA RHDPRLVIRP TAEPRLTRRI KLVIPEEQLS LPPVRHFRQL CREAMTAELC
     DFKTLSQLF