ID   NTD_LIMFE               Reviewed;         168 AA.
AC   Q6YNI5;
DT   13-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Nucleoside deoxyribosyltransferase;
DE            Short=N-deoxyribosyltransferase;
DE            EC=2.4.2.6;
GN   Name=ntd;
OS   Limosilactobacillus fermentum (Lactobacillus fermentum).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=1613;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14931 / DSM 20052 / JCM 1173 / NBRC 15885 / NCDO 1750 / NCIMB
RC   11840 / NRRL B-4524 / Bb28;
RA   Kaminski P.A.;
RT   "Characteriztion of the Lactobacillus fermentum N-
RT   deoxyribosyltransferase.";
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the cleavage of the glycosidic bond of 2'-
CC       deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an
CC       acceptor purine or pyrimidine base. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-deoxy-D-ribosyl-base(1) + base(2) = 2-deoxy-D-ribosyl-
CC         base(2) + base(1).; EC=2.4.2.6;
CC   -!- PATHWAY: Nucleotide metabolism; nucleotide salvage pathway.
CC   -!- SIMILARITY: Belongs to the nucleoside deoxyribosyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; AY064168; AAL73115.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6YNI5; -.
DR   SMR; Q6YNI5; -.
DR   BRENDA; 2.4.2.6; 2856.
DR   UniPathway; UPA00312; -.
DR   GO; GO:0050144; F:nucleoside deoxyribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043173; P:nucleotide salvage; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR007710; Nucleoside_deoxyribTrfase.
DR   Pfam; PF05014; Nuc_deoxyrib_tr; 1.
PE   3: Inferred from homology;
KW   Nucleotide metabolism; Transferase.
FT   CHAIN           1..168
FT                   /note="Nucleoside deoxyribosyltransferase"
FT                   /id="PRO_0000220065"
FT   ACT_SITE        103
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   168 AA;  18896 MW;  362162F43586C317 CRC64;
     MKNTDPVANT KIYLATSFFN EEQRARIPQA LAQLEANPTV GVVHQPFDFQ YKDARVDSDP
     AGVFGSLEWQ IATYNNDLNA VGTSDVCVAL YDMDQIDEGI CMEIGMFVAL HKPIVLLPFT
     KKDKSAYEAN LMLARGVTTW LEPNDFSPLK DFNFNHPMAQ PFPPFKVF