ID   NTF2_ASHGO              Reviewed;         125 AA.
AC   Q75AA5;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Nuclear transport factor 2;
DE            Short=NTF-2;
GN   Name=NTF2; OrderedLocusNames=ADR013W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Facilitates protein transport into the nucleus. Could be part
CC       of a multicomponent system of cytosolic factors that assemble at the
CC       pore complex during nuclear import (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AE016817; AAS51933.1; -; Genomic_DNA.
DR   RefSeq; NP_984109.1; NM_209462.1.
DR   AlphaFoldDB; Q75AA5; -.
DR   SMR; Q75AA5; -.
DR   STRING; 33169.AAS51933; -.
DR   EnsemblFungi; AAS51933; AAS51933; AGOS_ADR013W.
DR   GeneID; 4620258; -.
DR   KEGG; ago:AGOS_ADR013W; -.
DR   eggNOG; KOG2104; Eukaryota.
DR   HOGENOM; CLU_131642_0_0_1; -.
DR   InParanoid; Q75AA5; -.
DR   OMA; FTEFYYN; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:EnsemblFungi.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..125
FT                   /note="Nuclear transport factor 2"
FT                   /id="PRO_0000194782"
FT   DOMAIN          8..121
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   125 AA;  14421 MW;  4C8FD62F9267C924 CRC64;
     MSMDFSALAQ QFTEFYYNQF DTDRSQLGNL YRDQSMLTFE TSQLQGAKDI VEKLVSLPFQ
     KVQHRITTLD AQPASPNGDV LVMITGDLLI DDEQNAQRFS QVFHLMPEGN SYYVFNDIFR
     LNYSA