ID   NTF2_CAEEL              Reviewed;         133 AA.
AC   Q21735;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Probable nuclear transport factor 2;
DE            Short=NTF-2;
GN   Name=ran-4; ORFNames=R05D11.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Facilitates protein transport into the nucleus. Could be part
CC       of a multicomponent system of cytosolic factors that assemble at the
CC       pore complex during nuclear import (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; Z75546; CAA99890.1; -; Genomic_DNA.
DR   PIR; T23921; T23921.
DR   RefSeq; NP_492322.1; NM_059921.4.
DR   AlphaFoldDB; Q21735; -.
DR   SMR; Q21735; -.
DR   BioGRID; 38081; 15.
DR   IntAct; Q21735; 4.
DR   STRING; 6239.R05D11.3; -.
DR   EPD; Q21735; -.
DR   PaxDb; Q21735; -.
DR   PeptideAtlas; Q21735; -.
DR   EnsemblMetazoa; R05D11.3.1; R05D11.3.1; WBGene00004305.
DR   GeneID; 172648; -.
DR   KEGG; cel:CELE_R05D11.3; -.
DR   UCSC; R05D11.3.1; c. elegans.
DR   CTD; 172648; -.
DR   WormBase; R05D11.3; CE06238; WBGene00004305; ran-4.
DR   eggNOG; KOG2104; Eukaryota.
DR   GeneTree; ENSGT00510000047030; -.
DR   HOGENOM; CLU_131642_1_0_1; -.
DR   InParanoid; Q21735; -.
DR   OMA; FTEFYYN; -.
DR   OrthoDB; 1437819at2759; -.
DR   PhylomeDB; Q21735; -.
DR   PRO; PR:Q21735; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00004305; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..133
FT                   /note="Probable nuclear transport factor 2"
FT                   /id="PRO_0000194779"
FT   DOMAIN          10..128
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   133 AA;  15116 MW;  B283AA46AD59C7F2 CRC64;
     MSFNPDYESV AKAFIQHYYS KFDVGDGMSR AQGLSDLYDP ENSYMTFEGQ QAKGRDGILQ
     KFTTLGFTKI QRAITVIDSQ PLYDGSIQVM VLGQLKTDED PINPFSQVFI LRPNNQGSYF
     IGNEIFRLDL HNN