ID   NTF2_DAVTA              Reviewed;         125 AA.
AC   Q8NJ52;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Nuclear transport factor 2;
DE            Short=NTF-2;
DE   AltName: Allergen=Cla h ?;
GN   Name=NTF2;
OS   Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Cladosporiales; Cladosporiaceae; Cladosporium.
OX   NCBI_TaxID=29918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND ALLERGEN.
RC   STRAIN=280202-Berlin;
RX   PubMed=12653793; DOI=10.1034/j.1398-9995.2003.23822.x;
RA   Weichel M., Schmid-Grendelmeier P., Flueckiger S., Breitenbach M.,
RA   Blaser K., Crameri R.;
RT   "Nuclear transport factor 2 represents a novel cross-reactive fungal
RT   allergen.";
RL   Allergy 58:198-206(2003).
CC   -!- FUNCTION: Facilitates protein transport into the nucleus. Could be part
CC       of a multicomponent system of cytosolic factors that assemble at the
CC       pore complex during nuclear import (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE. Elicit
CC       type I skin reactions in mould-sensitized individuals.
CC       {ECO:0000269|PubMed:12653793}.
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DR   EMBL; AJ493279; CAD38166.1; -; mRNA.
DR   AlphaFoldDB; Q8NJ52; -.
DR   SMR; Q8NJ52; -.
DR   Allergome; 993; Cla h NTF2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   1: Evidence at protein level;
KW   Allergen; Cytoplasm; Protein transport; Transport.
FT   CHAIN           1..125
FT                   /note="Nuclear transport factor 2"
FT                   /id="PRO_0000194785"
FT   DOMAIN          7..120
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ   SEQUENCE   125 AA;  14156 MW;  9FDEA9F3B0653D02 CRC64;
     MSDFNAIAQQ FTEFYYKTFD TDRAQLAPLY RENSMLTFEQ SPFLGTANIV GKLQELPFQR
     IEHQVATVDA QPSNESGGIL VVVSGALLVE EERRPMSYTQ TFQLLPADGA YYVFNDVFRL
     VYPAA