NTF2_SCHPO
ID NTF2_SCHPO Reviewed; 123 AA.
AC Q10100; Q9UTF4;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2001, sequence version 2.
DT 25-MAY-2022, entry version 127.
DE RecName: Full=Nuclear transport factor 2;
DE Short=NTF-2;
GN Name=ntf2; ORFNames=SPAC15F9.03c, SPAC1B9.01c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Facilitates protein transport into the nucleus. Could be part
CC of a multicomponent system of cytosolic factors that assemble at the
CC pore complex during nuclear import (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR EMBL; CU329670; CAA92380.2; -; Genomic_DNA.
DR PIR; T38039; T38039.
DR RefSeq; XP_001713065.1; XM_001713013.2.
DR AlphaFoldDB; Q10100; -.
DR SMR; Q10100; -.
DR BioGRID; 279232; 1.
DR STRING; 4896.SPAC15F9.03c.1; -.
DR PaxDb; Q10100; -.
DR EnsemblFungi; SPAC15F9.03c.1; SPAC15F9.03c.1:pep; SPAC15F9.03c.
DR PomBase; SPAC15F9.03c; -.
DR VEuPathDB; FungiDB:SPAC15F9.03c; -.
DR eggNOG; KOG2104; Eukaryota.
DR HOGENOM; CLU_131642_0_0_1; -.
DR InParanoid; Q10100; -.
DR OMA; FTEFYYN; -.
DR PhylomeDB; Q10100; -.
DR PRO; PR:Q10100; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005635; C:nuclear envelope; HDA:PomBase.
DR GO; GO:0031965; C:nuclear membrane; ISO:PomBase.
DR GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0031267; F:small GTPase binding; ISO:PomBase.
DR GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR GO; GO:0006606; P:protein import into nucleus; ISO:PomBase.
DR CDD; cd00780; NTF2; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR045875; NTF2/Mtr2.
DR InterPro; IPR002075; NTF2_dom.
DR InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR PANTHER; PTHR12612; PTHR12612; 1.
DR Pfam; PF02136; NTF2; 1.
DR SUPFAM; SSF54427; SSF54427; 1.
DR PROSITE; PS50177; NTF2_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Protein transport; Reference proteome; Transport.
FT CHAIN 1..123
FT /note="Nuclear transport factor 2"
FT /id="PRO_0000194790"
FT DOMAIN 7..120
FT /note="NTF2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
SQ SEQUENCE 123 AA; 14078 MW; F587303CAA3270E6 CRC64;
MADYNALATQ FTQFYYQTFD SDRSQLSSLY REESMLSFEG AQLQGTKAIV EKLVSLPFQR
VQHRISTLDA QPTGTTGSVI VMVTGELLLD EEQMAQRYSQ VFHLVNNNGN YYVLNDLFRL
NYG