ID   NTF2_YARLI              Reviewed;         123 AA.
AC   Q6CC82; Q9P8H0;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Nuclear transport factor 2;
DE            Short=NTF-2;
GN   Name=NTF2; Synonyms=RPH1; OrderedLocusNames=YALI0C11605g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Cordero-Otero R.R., Lepingle A., Gaillardin C.;
RT   "RPH1 gene from Yarrowia lipolytica.";
RL   Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Facilitates protein transport into the nucleus. Could be part
CC       of a multicomponent system of cytosolic factors that assemble at the
CC       pore complex during nuclear import (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AF260231; AAF70316.1; -; Genomic_DNA.
DR   EMBL; CR382129; CAG82040.1; -; Genomic_DNA.
DR   RefSeq; XP_501730.1; XM_501730.1.
DR   AlphaFoldDB; Q6CC82; -.
DR   SMR; Q6CC82; -.
DR   STRING; 4952.CAG82040; -.
DR   EnsemblFungi; CAG82040; CAG82040; YALI0_C11605g.
DR   GeneID; 2909433; -.
DR   KEGG; yli:YALI0C11605g; -.
DR   VEuPathDB; FungiDB:YALI0_C11605g; -.
DR   HOGENOM; CLU_131642_0_0_1; -.
DR   InParanoid; Q6CC82; -.
DR   OMA; FTEFYYN; -.
DR   Proteomes; UP000001300; Chromosome C.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0044613; C:nuclear pore central transport channel; IBA:GO_Central.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   CDD; cd00780; NTF2; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR045875; NTF2/Mtr2.
DR   InterPro; IPR002075; NTF2_dom.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   PANTHER; PTHR12612; PTHR12612; 1.
DR   Pfam; PF02136; NTF2; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..123
FT                   /note="Nuclear transport factor 2"
FT                   /id="PRO_0000194791"
FT   DOMAIN          8..121
FT                   /note="NTF2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00137"
FT   CONFLICT        100
FT                   /note="A -> G (in Ref. 1; AAF70316)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   123 AA;  13710 MW;  9E0AB95CF0058255 CRC64;
     MSVDFNTLAK QFCEFYYQTF DTDRSQLGNL YRDHSMLTFT GTQHQGAQAI VEKLVGLPFG
     QVRHKISDID AQPASAQGGD VIVLVTGELC VDGDNPLPYA QVFHLIPDGS SYYVFNDIFR
     LNA