NTN1_PHYNA
ID NTN1_PHYNA Reviewed; 30 AA.
AC P86913;
DT 15-FEB-2017, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2017, sequence version 1.
DT 25-MAY-2022, entry version 7.
DE RecName: Full=Nattererin-1 {ECO:0000303|PubMed:26443407};
OS Physalaemus nattereri (Cuyaba dwarf frog) (Eupemphix nattereri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Hyloidea; Leptodactylidae; Leiuperinae;
OC Physalaemus.
OX NCBI_TaxID=248869 {ECO:0000303|PubMed:26443407};
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, PROBABLE FUNCTION, SUBCELLULAR LOCATION, MASS
RP SPECTROMETRY, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC TISSUE=Skin secretion {ECO:0000303|PubMed:26443407};
RX PubMed=26443407; DOI=10.1002/rcm.7313;
RA Barbosa E.A., Iembo T., Martins G.R., Silva L.P., Prates M.V.,
RA Andrade A.C., Bloch C. Jr.;
RT "Skin secretion peptides: the molecular facet of the deimatic behavior of
RT the four-eyed frog, Physalaemus nattereri (Anura, Leptodactylidae).";
RL Rapid Commun. Mass Spectrom. 29:2061-2068(2015).
CC -!- FUNCTION: Probably has antibacterial activity.
CC {ECO:0000269|PubMed:26443407}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26443407}.
CC -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC {ECO:0000305|PubMed:26443407}.
CC -!- MASS SPECTROMETRY: Mass=3179.79; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:26443407};
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DR AlphaFoldDB; P86913; -.
DR SMR; P86913; -.
DR GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amphibian defense peptide; Antibiotic; Antimicrobial;
KW Direct protein sequencing; Secreted.
FT PEPTIDE 1..30
FT /note="Nattererin-1"
FT /evidence="ECO:0000269|PubMed:26443407"
FT /id="PRO_0000438962"
SQ SEQUENCE 30 AA; 3181 MW; 4ADEE263EBF67900 CRC64;
GLKDMIKNLA KEAAVKLAGA VINKFSPQPQ