ID   NTN2_PHYNA              Reviewed;          30 AA.
AC   P86914;
DT   15-FEB-2017, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2017, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=Nattererin-2 {ECO:0000303|PubMed:26443407};
OS   Physalaemus nattereri (Cuyaba dwarf frog) (Eupemphix nattereri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Hyloidea; Leptodactylidae; Leiuperinae;
OC   Physalaemus.
OX   NCBI_TaxID=248869 {ECO:0000303|PubMed:26443407};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, PROBABLE FUNCTION, SUBCELLULAR LOCATION, MASS
RP   SPECTROMETRY, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC   TISSUE=Skin secretion {ECO:0000303|PubMed:26443407};
RX   PubMed=26443407; DOI=10.1002/rcm.7313;
RA   Barbosa E.A., Iembo T., Martins G.R., Silva L.P., Prates M.V.,
RA   Andrade A.C., Bloch C. Jr.;
RT   "Skin secretion peptides: the molecular facet of the deimatic behavior of
RT   the four-eyed frog, Physalaemus nattereri (Anura, Leptodactylidae).";
RL   Rapid Commun. Mass Spectrom. 29:2061-2068(2015).
CC   -!- FUNCTION: Probably has antibacterial activity.
CC       {ECO:0000269|PubMed:26443407}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26443407}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC       {ECO:0000305|PubMed:26443407}.
CC   -!- MASS SPECTROMETRY: Mass=3207.80; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:26443407};
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DR   AlphaFoldDB; P86914; -.
DR   SMR; P86914; -.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amphibian defense peptide; Antibiotic; Antimicrobial;
KW   Direct protein sequencing; Secreted.
FT   PEPTIDE         1..30
FT                   /note="Nattererin-2"
FT                   /evidence="ECO:0000269|PubMed:26443407"
FT                   /id="PRO_0000438963"
SQ   SEQUENCE   30 AA;  3209 MW;  4ADEE263EBF66E30 CRC64;
     GLKDMIKNLA KEAAVKLAGA VINRFSPQPQ