NTND_NECSZ
ID NTND_NECSZ Reviewed; 609 AA.
AC A0A455LLW5;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 05-JUN-2019, sequence version 1.
DT 25-MAY-2022, entry version 8.
DE RecName: Full=Transcription factor ntnD {ECO:0000303|PubMed:29797385};
DE AltName: Full=Nectripenoid biosynthesis cluster protein D {ECO:0000303|PubMed:29797385};
DE Flags: Fragment;
GN Name=ntnD {ECO:0000303|PubMed:29797385};
OS Nectria sp.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Nectria.
OX NCBI_TaxID=1755444;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND PATHWAY.
RC STRAIN=Z14-w;
RX PubMed=29797385; DOI=10.1002/anie.201804317;
RA Zhang X., Wang T.T., Xu Q.L., Xiong Y., Zhang L., Han H., Xu K., Guo W.J.,
RA Xu Q., Tan R.X., Ge H.M.;
RT "Genome mining and comparative biosynthesis of meroterpenoids from two
RT phylogenetically distinct fungi.";
RL Angew. Chem. Int. Ed. 57:8184-8188(2018).
CC -!- FUNCTION: Transcription factor; part of the gene cluster that mediates
CC the biosynthesis of meroterpenoids. {ECO:0000269|PubMed:29797385}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TRI10 transcription regulator family.
CC {ECO:0000305}.
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DR EMBL; MH182998; AYO60865.1; -; mRNA.
DR AlphaFoldDB; A0A455LLW5; -.
DR SMR; A0A455LLW5; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR021858; Fun_TF.
DR Pfam; PF11951; Fungal_trans_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Transcription;
KW Transcription regulation; Zinc.
FT CHAIN <1..609
FT /note="Transcription factor ntnD"
FT /id="PRO_0000452564"
FT DNA_BIND <1..7
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000305"
FT REGION 46..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000305"
SQ SEQUENCE 609 AA; 69113 MW; 460BDD1F90E1A6FF CRC64;
MCVGIECHGF GDKPAWMDRG ARQKAEAAKM KQKVTQVARN RRMNQFRDQN ESSLNRIHNR
RTSNSQPSTR SINNTTTIPA SNNEPLALSQ PPSASSQNQV EKDQLSTYHQ DSINVAIDPL
DTIDSSLPDF QTVFDEINFL TDQTFDLPEI DWTSTNNVPI TDNTANMGVT NGLRAGQYVP
RSQKQIDMDF SPRDSPSMLT ISDVEDAALL AYYVSKVFHW QFRFCSSTMS GFNQGYFIWL
MSKSRPLYLA SLALSSSYRS FQNNAKEPQP CLKYEEHMQR YDIATEELQG HLKGHTPMND
VTMLACIVSF ISSSFLHSGR IDGNVHLKAG VSLIAPRISR QQSGTLSDVH KTPEESSRDF
LTGSIIRFDI LSAITRDTVP SLSDSYRRIL RSSSPSILLE TVSGCQNWVF DILLDVYALR
DWKRNTRAVG LLSLWELTAK ANMIKSDLER RITSNLMLMN ESKQEVKTQE DENLQSRHYK
HEICVVTHTF ACAVSILLEV IVSGAYPQVP EIKQKVGRAL ESFAYIEDPD ILEVLTWPLF
VVGCVVEEDH HECFRQLLSS TQLVRSIGLY GLKEILEKCW KSRETGEIKD ESFDFSHFHT
YKSREILIA