ID   NTP4_TOXGO              Reviewed;         592 AA.
AC   P52913;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Putative nucleoside-triphosphatase;
DE            Short=NTPase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
GN   Name=NTP4;
OS   Toxoplasma gondii.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX   NCBI_TaxID=5811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Nicole;
RA   Cote S., Morency M., Levesque R.C.;
RL   Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-
CC         diphosphate + H(+) + phosphate; Xref=Rhea:RHEA:23680,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15;
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. It does not seem to
CC       start with an initiator Met. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA80336.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U28353; AAA80336.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; P52913; -.
DR   SMR; P52913; -.
DR   VEuPathDB; ToxoDB:TGARI_371290; -.
DR   VEuPathDB; ToxoDB:TGCAST_358870; -.
DR   VEuPathDB; ToxoDB:TGCOUG_395210; -.
DR   VEuPathDB; ToxoDB:TGDOM2_278878; -.
DR   VEuPathDB; ToxoDB:TGDOM2_400630; -.
DR   VEuPathDB; ToxoDB:TGFOU_278882; -.
DR   VEuPathDB; ToxoDB:TGGT1_277270; -.
DR   VEuPathDB; ToxoDB:TGGT1_408820; -.
DR   VEuPathDB; ToxoDB:TGMAS_363610; -.
DR   VEuPathDB; ToxoDB:TGMAS_364050; -.
DR   VEuPathDB; ToxoDB:TGME49_278882; -.
DR   VEuPathDB; ToxoDB:TGP89_358330; -.
DR   VEuPathDB; ToxoDB:TGP89_422570; -.
DR   VEuPathDB; ToxoDB:TGPRC2_358870; -.
DR   VEuPathDB; ToxoDB:TGRH88_066180; -.
DR   VEuPathDB; ToxoDB:TGRUB_278882; -.
DR   VEuPathDB; ToxoDB:TGVAND_278882; -.
DR   VEuPathDB; ToxoDB:TGVEG_360830; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   InterPro; IPR017227; NTPase_alveloata.
DR   PANTHER; PTHR11782; PTHR11782; 1.
DR   Pfam; PF01150; GDA1_CD39; 1.
DR   PIRSF; PIRSF037506; NTPase; 1.
DR   PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE   5: Uncertain;
KW   Hydrolase.
FT   CHAIN           1..592
FT                   /note="Putative nucleoside-triphosphatase"
FT                   /id="PRO_0000209922"
FT   ACT_SITE        200
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   592 AA;  65762 MW;  B0C4014049F8D79B CRC64;
     LPEKRINVGK KHLQTLRNLE TRCHDSFQAF VVIDARSSST RTNVFLAKTR SCPNRGRSID
     PDSIRLIREG KRFTGLRVVL EEWLDTYAGK DWESRPVDAR LLFQYVPQMH EGAKKPMQLL
     EEDTVAILDS QLNEKQKVQV KALGIPAMLC STAGVRDFHE WYRDALFVLL RHLINNPSPA
     HGYKFFTNPF WTRPITGAEE GLFAFITLNH LSRRLGEDPA RCMIDEYGVK QCRNDLAGVV
     EVGGASAQIV FPLQEGTVLP SSVRAVNLQR ERLLPERYPS ADVVSVSFMQ LGMASSAGLF
     LKELCSNDEF LQGGICSNPC LFKGFQQSCS AGEVEVRPDG SASVNEDVRK NRLKPLATYC
     SVNNPEISFK VTNEMQCREN SIDPTKPLAE RMKIENCSII KGTGNFDKCV SQVESILVAP
     KLPLPANIEA ASSGFESVDQ VFRFASSTAP MIVTGGGMLA AINTLKDHRL LRSDFSGDVE
     ELAEAAREFC SSEVIIRTDG PVIQLPNARG EQKLNSLNFD LCKTMALTVS LLRHMAAGEN
     QPSFIKWEKS IAGPDGKPLA DLGWQVGVIL HHVLFTEEWG RNAYEAGYSH NL