ID   NTPA_PEA                Reviewed;         455 AA.
AC   P52914;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            Short=NTPase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=Apyrase;
OS   Pisum sativum (Garden pea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX   NCBI_TaxID=3888;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Alaska; TISSUE=Plumule;
RX   PubMed=8616230; DOI=10.1007/bf00017808;
RA   Hsieh H., Tong C.G., Thomas C., Roux S.J.;
RT   "Light-modulated abundance of an mRNA encoding a calmodulin-regulated,
RT   chromatin-associated NTPase in pea.";
RL   Plant Mol. Biol. 30:135-147(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Alaska; TISSUE=Stem;
RX   PubMed=12238526; DOI=10.1007/s11738-001-0016-y;
RA   Shibata K., Abe S., Davies E.;
RT   "Structure of the coding region and mRNA variants of the apyrase gene from
RT   pea (Pisum sativum).";
RL   Acta Physiol. Plant. 23:3-13(2001).
CC   -!- FUNCTION: Might be involved in RNA transport out of nuclei.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-
CC         diphosphate + H(+) + phosphate; Xref=Rhea:RHEA:23680,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15;
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family. {ECO:0000305}.
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DR   EMBL; Z32743; CAA83655.1; -; mRNA.
DR   EMBL; AB027614; BAB18900.1; -; mRNA.
DR   PIR; S65147; S48859.
DR   AlphaFoldDB; P52914; -.
DR   SMR; P52914; -.
DR   EnsemblPlants; Psat3g090960.1; Psat3g090960.1.cds; Psat3g090960.
DR   Gramene; Psat3g090960.1; Psat3g090960.1.cds; Psat3g090960.
DR   KEGG; ag:CAA83655; -.
DR   BioCyc; MetaCyc:MON-17880; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:RHEA.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   PANTHER; PTHR11782; PTHR11782; 1.
DR   Pfam; PF01150; GDA1_CD39; 1.
DR   PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; mRNA transport; Nucleus; Transport.
FT   CHAIN           1..455
FT                   /note="Nucleoside-triphosphatase"
FT                   /id="PRO_0000209921"
FT   ACT_SITE        168
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   455 AA;  50072 MW;  50FDF0023ABC4299 CRC64;
     MELLIKLITF LLFSMPAITS SQYLGNNLLT SRKIFLKQEE ISSYAVVFDA GSTGSRIHVY
     HFNQNLDLLH IGKGVEYYNK ITPGLSSYAN NPEQAAKSLI PLLEQAEDVV PDDLQPKTPV
     RLGATAGLRL LNGDASEKIL QSVRDMLSNR STFNVQPDAV SIIDGTQEGS YLWVTVNYAL
     GNLGKKYTKT VGVIDLGGGS VQMAYAVSKK TAKNAPKVAD GDDPYIKKVV LKGIPYDLYV
     HSYLHFGREA SRAEILKLTP RSPNPCLLAG FNGIYTYSGE EFKATAYTSG ANFNKCKNTI
     RKALKLNYPC PYQNCTFGGI WNGGGGNGQK NLFASSSFFY LPEDTGMVDA STPNFILRPV
     DIETKAKEAC ALNFEDAKST YPFLDKKNVA SYVCMDLIYQ YVLLVDGFGL DPLQKITSGK
     EIEYQDAIVE AAWPLGNAVE AISALPKFER LMYFV