NTPG_ENTHA
ID NTPG_ENTHA Reviewed; 103 AA.
AC P43455; I6SD39;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=V-type sodium ATPase subunit G;
DE AltName: Full=Na(+)-translocating ATPase subunit G;
DE AltName: Full=V-type sodium pump subunit G;
GN Name=ntpG; Synonyms=ntpQ; OrderedLocusNames=EHR_08255;
OS Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 /
OS NBRC 3181 / NCIMB 6459 / NCDO 1258 / NCTC 12367 / WDCM 00089 / R).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=768486;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459
RC / NCDO 1258 / NCTC 12367 / WDCM 00089 / R;
RX PubMed=8157629; DOI=10.1016/s0021-9258(19)78088-0;
RA Takase K., Kakinuma S., Yamato I., Konishi K., Igarashi K., Kakinuma Y.;
RT "Sequencing and characterization of the ntp gene cluster for vacuolar-type
RT Na(+)-translocating ATPase of Enterococcus hirae.";
RL J. Biol. Chem. 269:11037-11044(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459
RC / NCDO 1258 / NCTC 12367 / WDCM 00089 / R;
RX PubMed=8144530; DOI=10.1016/s0021-9258(17)36902-8;
RA Solioz M., Davies K.;
RT "Operon of vacuolar-type Na(+)-ATPase of Enterococcus hirae.";
RL J. Biol. Chem. 269:9453-9459(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459
RC / NCDO 1258 / NCTC 12367 / WDCM 00089 / R;
RX PubMed=22933757; DOI=10.1128/jb.01075-12;
RA Gaechter T., Wunderlin C., Schmidheini T., Solioz M.;
RT "Genome sequence of Enterococcus hirae (Streptococcus faecalis) ATCC 9790,
RT a model organism for the study of ion transport, bioenergetics, and copper
RT homeostasis.";
RL J. Bacteriol. 194:5126-5127(2012).
CC -!- FUNCTION: Involved in ATP-driven sodium extrusion.
CC -!- SIMILARITY: Belongs to the V-ATPase F subunit family. {ECO:0000305}.
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DR EMBL; D17462; BAA04274.1; -; Genomic_DNA.
DR EMBL; X76913; CAA54240.1; -; Genomic_DNA.
DR EMBL; CP003504; AFM70578.1; -; Genomic_DNA.
DR PIR; F54392; F54392.
DR RefSeq; WP_010718638.1; NZ_KB946231.1.
DR PDB; 3AON; X-ray; 2.00 A; B=1-103.
DR PDB; 3VR4; X-ray; 2.17 A; H=1-103.
DR PDB; 3VR5; X-ray; 3.90 A; H=1-103.
DR PDB; 3VR6; X-ray; 2.68 A; H=1-103.
DR PDB; 5KNB; X-ray; 3.25 A; H=1-103.
DR PDB; 5KNC; X-ray; 3.02 A; H=1-103.
DR PDB; 5KND; X-ray; 2.89 A; H=1-103.
DR PDBsum; 3AON; -.
DR PDBsum; 3VR4; -.
DR PDBsum; 3VR5; -.
DR PDBsum; 3VR6; -.
DR PDBsum; 5KNB; -.
DR PDBsum; 5KNC; -.
DR PDBsum; 5KND; -.
DR AlphaFoldDB; P43455; -.
DR SMR; P43455; -.
DR DIP; DIP-59797N; -.
DR IntAct; P43455; 2.
DR STRING; 768486.EHR_08255; -.
DR TCDB; 3.A.2.2.2; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR EnsemblBacteria; AFM70578; AFM70578; EHR_08255.
DR GeneID; 66464793; -.
DR KEGG; ehr:EHR_08255; -.
DR eggNOG; COG1436; Bacteria.
DR HOGENOM; CLU_135754_1_0_9; -.
DR OrthoDB; 1997116at2; -.
DR BioCyc; MetaCyc:MON-14152; -.
DR Proteomes; UP000002895; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.10580; -; 1.
DR HAMAP; MF_00312; ATP_synth_F_arch; 1.
DR InterPro; IPR008218; ATPase_V1-cplx_f_g_su.
DR InterPro; IPR022944; ATPase_V1-cplx_fsu_bac/arc.
DR InterPro; IPR036906; ATPase_V1_fsu_sf.
DR Pfam; PF01990; ATP-synt_F; 1.
DR SUPFAM; SSF159468; SSF159468; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Ion transport; Sodium; Sodium transport; Transport.
FT CHAIN 1..103
FT /note="V-type sodium ATPase subunit G"
FT /id="PRO_0000144830"
FT STRAND 2..9
FT /evidence="ECO:0007829|PDB:3AON"
FT HELIX 11..14
FT /evidence="ECO:0007829|PDB:3AON"
FT HELIX 15..20
FT /evidence="ECO:0007829|PDB:3AON"
FT STRAND 23..25
FT /evidence="ECO:0007829|PDB:3AON"
FT HELIX 30..42
FT /evidence="ECO:0007829|PDB:3AON"
FT STRAND 45..51
FT /evidence="ECO:0007829|PDB:3AON"
FT HELIX 52..55
FT /evidence="ECO:0007829|PDB:3AON"
FT HELIX 59..66
FT /evidence="ECO:0007829|PDB:3AON"
FT STRAND 68..70
FT /evidence="ECO:0007829|PDB:3AON"
FT STRAND 72..76
FT /evidence="ECO:0007829|PDB:3AON"
FT HELIX 85..97
FT /evidence="ECO:0007829|PDB:3AON"
SQ SEQUENCE 103 AA; 11410 MW; 5F452721633D3960 CRC64;
MTYKIGVVGD KDSVSPFRLF GFDVQHGTTK TEIRKTIDEM AKNEYGVIYI TEQCANLVPE
TIERYKGQLT PAIILIPSHQ GTLGIGLEEI QNSVEKAVGQ NIL
