14312_ARATH
ID 14312_ARATH Reviewed; 268 AA.
AC Q9C5W6; Q541X6; Q8LEN1; Q9FZD3;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=14-3-3-like protein GF14 iota {ECO:0000303|PubMed:11553742};
DE AltName: Full=General regulatory factor 12 {ECO:0000303|PubMed:11553742};
GN Name=GRF12 {ECO:0000303|PubMed:11553742};
GN OrderedLocusNames=At1g26480 {ECO:0000312|Araport:AT1G26480};
GN ORFNames=T1K7.15 {ECO:0000312|EMBL:AAF98570.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=11553742; DOI=10.1104/pp.127.1.142;
RA Rosenquist M., Alsterfjord M., Larsson C., Sommarin M.;
RT "Data mining the Arabidopsis genome reveals fifteen 14-3-3 genes.
RT Expression is demonstrated for two out of five novel genes.";
RL Plant Physiol. 127:142-149(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Is associated with a DNA binding complex that binds to the G
CC box, a well-characterized cis-acting DNA regulatory element found in
CC plant genes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P48349}. Cytoplasm
CC {ECO:0000250|UniProtKB:P48349}. Note=Translocates from the cytosol to
CC the nucleus when phosphorylated. {ECO:0000250|UniProtKB:P48349}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers.
CC {ECO:0000269|PubMed:11553742}.
CC -!- SIMILARITY: Belongs to the 14-3-3 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM62569.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF335544; AAK11271.1; -; mRNA.
DR EMBL; AC013427; AAF98570.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30696.1; -; Genomic_DNA.
DR EMBL; AK117907; BAC42545.1; -; mRNA.
DR EMBL; BT006230; AAP12879.1; -; mRNA.
DR EMBL; AY085338; AAM62569.1; ALT_INIT; mRNA.
DR PIR; F86391; F86391.
DR RefSeq; NP_564249.1; NM_102411.3.
DR AlphaFoldDB; Q9C5W6; -.
DR SMR; Q9C5W6; -.
DR BioGRID; 24425; 12.
DR IntAct; Q9C5W6; 2.
DR STRING; 3702.AT1G26480.1; -.
DR iPTMnet; Q9C5W6; -.
DR PaxDb; Q9C5W6; -.
DR PRIDE; Q9C5W6; -.
DR ProteomicsDB; 245147; -.
DR EnsemblPlants; AT1G26480.1; AT1G26480.1; AT1G26480.
DR GeneID; 839189; -.
DR Gramene; AT1G26480.1; AT1G26480.1; AT1G26480.
DR KEGG; ath:AT1G26480; -.
DR Araport; AT1G26480; -.
DR TAIR; locus:2197940; AT1G26480.
DR eggNOG; KOG0841; Eukaryota.
DR HOGENOM; CLU_058290_0_1_1; -.
DR InParanoid; Q9C5W6; -.
DR OMA; ERETHIY; -.
DR OrthoDB; 1176818at2759; -.
DR PhylomeDB; Q9C5W6; -.
DR PRO; PR:Q9C5W6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C5W6; baseline and differential.
DR Genevisible; Q9C5W6; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0008104; P:protein localization; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 1.20.190.20; -; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR023409; 14-3-3_CS.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; PTHR18860; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PIRSF; PIRSF000868; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; SSF48445; 1.
DR PROSITE; PS00796; 1433_1; 1.
DR PROSITE; PS00797; 1433_2; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..268
FT /note="14-3-3-like protein GF14 iota"
FT /id="PRO_0000058674"
FT REGION 240..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 70
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P48349"
FT MOD_RES 193
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P48349"
FT MOD_RES 214
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:P48349"
FT CONFLICT 268
FT /note="N -> VVIHFKMRTDQRAWKLNEI (in Ref. 2; AAF98570)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 268 AA; 30545 MW; 914F394CEC07A28C CRC64;
MSSSGSDKER ETFVYMAKLS EQAERYDEMV ETMKKVARVN SELTVEERNL LSVGYKNVIG
ARRASWRIMS SIEQKEESKG NESNVKQIKG YRQKVEDELA NICQDILTII DQHLIPHATS
GEATVFYYKM KGDYYRYLAE FKTEQERKEA AEQSLKGYEA ATQAASTELP STHPIRLGLA
LNFSVFYYEI MNSPERACHL AKQAFDEAIA ELDTLSEESY KDSTLIMQLL RDNLTLWTSD
LPEDGGEDNI KTEESKQEQA KPADATEN
