ID   NTRC_RHILP              Reviewed;          26 AA.
AC   P41502;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=DNA-binding transcriptional regulator NtrC {ECO:0000250|UniProtKB:P0AFB8};
DE   AltName: Full=Nitrogen regulation protein NR(I) {ECO:0000250|UniProtKB:P0AFB8};
DE   AltName: Full=Nitrogen regulator I {ECO:0000250|UniProtKB:P0AFB8};
DE            Short=NRI {ECO:0000250|UniProtKB:P0AFB8};
DE   Flags: Fragment;
GN   Name=ntrC;
OS   Rhizobium leguminosarum bv. phaseoli.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=385;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CE-3;
RX   PubMed=8412703; DOI=10.1111/j.1365-2958.1993.tb01717.x;
RA   Patriarca E.J., Riccio A., Tate R., Colonna-Romano S., Iaccarino M.,
RA   Defez R.;
RT   "The ntrBC genes of Rhizobium leguminosarum are part of a complex operon
RT   subject to negative regulation.";
RL   Mol. Microbiol. 9:569-577(1993).
CC   -!- FUNCTION: Member of the two-component regulatory system NtrB/NtrC,
CC       which controls expression of the nitrogen-regulated (ntr) genes in
CC       response to nitrogen limitation. Phosphorylated NtrC binds directly to
CC       DNA and stimulates the formation of open promoter-sigma54-RNA
CC       polymerase complexes. {ECO:0000250|UniProtKB:P0AFB8}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P0AFB8}.
CC   -!- PTM: Phosphorylated and dephosphorylated by NtrB.
CC       {ECO:0000250|UniProtKB:P0AFB8}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X71436; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S36203; S36203.
DR   AlphaFoldDB; P41502; -.
DR   SMR; P41502; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; ATP-binding; Cytoplasm; DNA-binding; Nitrogen fixation;
KW   Nucleotide-binding; Phosphoprotein; Repressor; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..>26
FT                   /note="DNA-binding transcriptional regulator NtrC"
FT                   /id="PRO_0000081172"
FT   DOMAIN          4..>26
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   NON_TER         26
SQ   SEQUENCE   26 AA;  2687 MW;  E11ECC63C8636304 CRC64;
     MTATILVADD DAAIRTVLNQ ALSRAG