ID   NTRI_BOVIN              Reviewed;         345 AA.
AC   Q58DA5; Q17QT6;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Neurotrimin;
DE   Flags: Precursor;
GN   Name=NTM; Synonyms=NT;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Neural cell adhesion molecule. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-
CC       anchor {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the immunoglobulin superfamily. IgLON family.
CC       {ECO:0000305}.
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DR   EMBL; BT021692; AAX46539.1; -; mRNA.
DR   EMBL; BC118192; AAI18193.1; -; mRNA.
DR   RefSeq; NP_001017949.1; NM_001017949.2.
DR   AlphaFoldDB; Q58DA5; -.
DR   SMR; Q58DA5; -.
DR   STRING; 9913.ENSBTAP00000013234; -.
DR   PaxDb; Q58DA5; -.
DR   Ensembl; ENSBTAT00000013234; ENSBTAP00000013234; ENSBTAG00000010032.
DR   GeneID; 534414; -.
DR   KEGG; bta:534414; -.
DR   CTD; 50863; -.
DR   VEuPathDB; HostDB:ENSBTAG00000010032; -.
DR   VGNC; VGNC:32302; NTM.
DR   eggNOG; KOG3510; Eukaryota.
DR   GeneTree; ENSGT00940000158679; -.
DR   HOGENOM; CLU_027228_2_2_1; -.
DR   InParanoid; Q58DA5; -.
DR   OMA; PITKRDF; -.
DR   OrthoDB; 583722at2759; -.
DR   TreeFam; TF325565; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000010032; Expressed in retina and 68 other tissues.
DR   ExpressionAtlas; Q58DA5; baseline.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   Pfam; PF07679; I-set; 1.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
DR   PROSITE; PS50835; IG_LIKE; 3.
PE   2: Evidence at transcript level;
KW   Cell adhesion; Cell membrane; Disulfide bond; Glycoprotein; GPI-anchor;
KW   Immunoglobulin domain; Lipoprotein; Membrane; Reference proteome; Repeat;
KW   Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..321
FT                   /note="Neurotrimin"
FT                   /id="PRO_0000239704"
FT   PROPEP          322..345
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000239705"
FT   DOMAIN          39..126
FT                   /note="Ig-like C2-type 1"
FT   DOMAIN          136..218
FT                   /note="Ig-like C2-type 2"
FT   DOMAIN          222..309
FT                   /note="Ig-like C2-type 3"
FT   LIPID           321
FT                   /note="GPI-anchor amidated asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        44
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        70
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        152
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        284
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        292
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        305
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        321
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        57..115
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   DISULFID        157..201
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   DISULFID        243..295
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
SQ   SEQUENCE   345 AA;  38000 MW;  47C94D781A70F0F7 CRC64;
     MGVCGSLFLP WKCLVVVSLR LLFLVPTGVP VRSGDATFPK AMDNVTVRQG ESATLRCTID
     NRVTRVAWLN RSTILYAGND KWCLDPRVVL LSNTQTQYSI EIQNVDVYDE GPYTCSVQTD
     NHPKTSRVHL IVQVSPKIVE ISSDISINEG NNISLTCIAT GRPEPTVTWR HISPKAVGFV
     SEDEYLEIQG ITREQSGYYE CSASNDVAAP VVRRVKVTVN YPPYISEAKG TGVPVGQKGT
     LQCEASAVPS AEFQWYKDDK RLVEGKKGVK VENRPFLSKL IFFNVSEHDY GNYTCVASNK
     LGHTNASITL FGPGAVSEVS NGTSSRRAGC LWLLPLLVLH LLLKF