ID   NTRXL_RICBR             Reviewed;         478 AA.
AC   Q1RJS1;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Putative response regulator NtrX-like;
GN   OrderedLocusNames=RBE_0312;
OS   Rickettsia bellii (strain RML369-C).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX   NCBI_TaxID=336407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RML369-C;
RX   PubMed=16703114; DOI=10.1371/journal.pgen.0020076;
RA   Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C.,
RA   Fournier P.-E., Claverie J.-M., Raoult D.;
RT   "Genome sequence of Rickettsia bellii illuminates the role of amoebae in
RT   gene exchanges between intracellular pathogens.";
RL   PLoS Genet. 2:733-744(2006).
CC   -!- FUNCTION: Member of the two-component regulatory system
CC       RBE_0312/RBE_0470. {ECO:0000250}.
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DR   EMBL; CP000087; ABE04393.1; -; Genomic_DNA.
DR   RefSeq; WP_011477004.1; NC_007940.1.
DR   AlphaFoldDB; Q1RJS1; -.
DR   SMR; Q1RJS1; -.
DR   STRING; 336407.RBE_0312; -.
DR   PRIDE; Q1RJS1; -.
DR   EnsemblBacteria; ABE04393; ABE04393; RBE_0312.
DR   KEGG; rbe:RBE_0312; -.
DR   eggNOG; COG2204; Bacteria.
DR   HOGENOM; CLU_000445_0_6_5; -.
DR   OMA; DWTGNIR; -.
DR   OrthoDB; 123059at2; -.
DR   Proteomes; UP000001951; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..478
FT                   /note="Putative response regulator NtrX-like"
FT                   /id="PRO_0000282381"
FT   DOMAIN          5..121
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          143..372
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         171..178
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         235..244
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   MOD_RES         54
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   478 AA;  54136 MW;  CD9CD2126484268C CRC64;
     MSLIDVLIVD DEEDIRNIIA AILKDEGFNP KVAANSTQAL KILAEKPVSA VILDIWLQGS
     EMDGLGILEV IKKRYPLMPV IIISGHGTIE TAVNAIKMGA YDYIEKPFNN DKLVILLKRA
     CEVTKLKREN IDLKSKVIDK TELVGNSTIT LKYKAEIDKA ASSSSRIMIH GKVGSGKELT
     ARLIHKKSKR VNNLFIIFSP TCMTLEKINQ ELFGEAEKQE SNNNSNKRPT ILEFANNGTL
     YIDEVSNIPV PIQIKLLKFL KDHTIKKPCG KIVKVDIKII TGTSKNIQEE VNNGRFLEDL
     YYRLNVSSLK VPSLFERKED IPLLVKYFVK QLSKFSGLKE RVFADETIAA LQSYEWPGNI
     RQLRNVVEWT LIMNPITSGN NEIIKPYMIP SEILANSVNL TKLEDSFDML SMPLREAREV
     FERQYLSAQM SRFNNNILKT SSFVGMERSA LHRKLKLLSL HIPPTGRINE EEYEEANA