NU107_ARATH
ID NU107_ARATH Reviewed; 1101 AA.
AC Q8L748; F4JFR3; F4JFR5; Q84ME0; Q9LJH6;
DT 26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Nuclear pore complex protein NUP107 {ECO:0000303|PubMed:21189294};
DE AltName: Full=Nucleoporin 107;
GN Name=NUP107 {ECO:0000303|PubMed:21189294};
GN OrderedLocusNames=At3g14120 {ECO:0000312|Araport:AT3G14120};
GN ORFNames=MAG2.7 {ECO:0000312|EMBL:BAB02976.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAM98082.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION IN THE NUCLEAR PORE COMPLEX BY MASS SPECTROMETRY,
RP SUBCELLULAR LOCATION, AND NOMENCLATURE.
RX PubMed=21189294; DOI=10.1105/tpc.110.079947;
RA Tamura K., Fukao Y., Iwamoto M., Haraguchi T., Hara-Nishimura I.;
RT "Identification and characterization of nuclear pore complex components in
RT Arabidopsis thaliana.";
RL Plant Cell 22:4084-4097(2010).
CC -!- SUBUNIT: Part of the nuclear pore complex (NPC). The NPC has an eight-
CC fold symmetrical structure comprising a central transport channel and
CC two rings, the cytoplasmic and nuclear rings, to which eight filaments
CC are attached. The cytoplasmic filaments have loose ends, while the
CC nuclear filaments are joined in a distal ring, forming a nuclear
CC basket. NPCs are highly dynamic in configuration and composition, and
CC can be devided in 3 subcomplexes, the NUP62 subcomplex, the NUP107-160
CC subcomplex and the NUP93 subcomplex, containing approximately 30
CC different nucleoporin proteins. {ECO:0000305|PubMed:21189294}.
CC -!- SUBCELLULAR LOCATION: Nucleus envelope {ECO:0000269|PubMed:21189294}.
CC Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q8L748-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8L748-2; Sequence=VSP_057122, VSP_057123;
CC Name=3;
CC IsoId=Q8L748-3; Sequence=VSP_057123;
CC -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02976.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP000600; BAB02976.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75472.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75473.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75474.1; -; Genomic_DNA.
DR EMBL; AY139761; AAM98082.1; -; mRNA.
DR EMBL; BT006367; AAP21175.1; -; mRNA.
DR RefSeq; NP_001189889.1; NM_001202960.1. [Q8L748-2]
DR RefSeq; NP_188028.2; NM_112268.3. [Q8L748-1]
DR RefSeq; NP_850581.1; NM_180250.3. [Q8L748-3]
DR AlphaFoldDB; Q8L748; -.
DR BioGRID; 5963; 16.
DR IntAct; Q8L748; 1.
DR STRING; 3702.AT3G14120.1; -.
DR iPTMnet; Q8L748; -.
DR PaxDb; Q8L748; -.
DR PRIDE; Q8L748; -.
DR ProteomicsDB; 248977; -. [Q8L748-1]
DR EnsemblPlants; AT3G14120.1; AT3G14120.1; AT3G14120. [Q8L748-1]
DR EnsemblPlants; AT3G14120.2; AT3G14120.2; AT3G14120. [Q8L748-3]
DR EnsemblPlants; AT3G14120.3; AT3G14120.3; AT3G14120. [Q8L748-2]
DR GeneID; 820629; -.
DR Gramene; AT3G14120.1; AT3G14120.1; AT3G14120. [Q8L748-1]
DR Gramene; AT3G14120.2; AT3G14120.2; AT3G14120. [Q8L748-3]
DR Gramene; AT3G14120.3; AT3G14120.3; AT3G14120. [Q8L748-2]
DR KEGG; ath:AT3G14120; -.
DR Araport; AT3G14120; -.
DR TAIR; locus:2087477; AT3G14120.
DR eggNOG; KOG1964; Eukaryota.
DR InParanoid; Q8L748; -.
DR OMA; EEDMPHE; -.
DR OrthoDB; 671846at2759; -.
DR PhylomeDB; Q8L748; -.
DR PRO; PR:Q8L748; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8L748; baseline and differential.
DR Genevisible; Q8L748; AT.
DR GO; GO:0005635; C:nuclear envelope; IDA:TAIR.
DR GO; GO:0031080; C:nuclear pore outer ring; IBA:GO_Central.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR GO; GO:0006406; P:mRNA export from nucleus; IBA:GO_Central.
DR GO; GO:0000973; P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR007252; Nup84/Nup107.
DR PANTHER; PTHR13003; PTHR13003; 1.
DR Pfam; PF04121; Nup84_Nup100; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; mRNA transport; Nuclear pore complex; Nucleus;
KW Protein transport; Reference proteome; Translocation; Transport.
FT CHAIN 1..1101
FT /note="Nuclear pore complex protein NUP107"
FT /id="PRO_0000431075"
FT VAR_SEQ 260
FT /note="K -> KCSSFNFHKQKLSKTVVAFSFL (in isoform 2)"
FT /id="VSP_057122"
FT VAR_SEQ 963..986
FT /note="Missing (in isoform 2 and isoform 3)"
FT /id="VSP_057123"
FT CONFLICT 987
FT /note="E -> D (in Ref. 3; AAP21175)"
SQ SEQUENCE 1101 AA; 125327 MW; 0C52F4003BF2DBBE CRC64;
MDMDMDTSPS YFDPEALSVR DQFRRYRKRH STSPHEEMLS SNVSENRLLY DGHNIHSPTN
TALLLENIKE EVDNFHTDHY EGTPTNPISA SRRESVGILN DDDEALFRRV ESQSLKACKI
ENDELAESGD TTFALFASLF DSALQGLMSI PNLMLRLEES CRNVSQSIRY GSDIRHRAVE
DKLMRQKAQL LLGEAASWSL LWNLYGKGTD EVPENLILIP STSHLEACQF VLNDHTAQLC
LRIVMWLEEL ASKSLDLERK VQGSHVGTYL PNAGVWHHTQ RYLKKNGSNA DTLHHLDFDA
PTREHARLLP DDYKQDESVL EDVWTLIRAG RIEEACDLCR SAGQSWRAAT LCPFSGMDMF
PSIEALVKNG ENRTLQAIEQ ESGFGNQLRL WKWASYCASE KIAEQDGGKH EVAVFATQCS
NLNRMLPICT DWESACWAMA KSWLDVQVDL ELAQSKPGLT ERFKSCIDES PEATQNGCQA
SFGPEDWPLH VLNQQPRDLP ALLQKLHSGE MVHEAVVRGC KEQHRQIQMN LMLGDISHLL
DIIWSWIAPL EDDQSNFRPH GDPHMIKFGA HMVLVLRLLF TDEINDSFKE KLNNVGDLIL
HMYAMFLFSK QHEELVGIYA SQLARHRCIE LFVHMMELRM HSSVHVKYKI FLSAMEYLSF
SPVDDLHGNF EEIVDRVLSR SREIKLAKYD PSIDVAEQHR QQSLQKAIAI QWLCFTPPST
IKDVKDVTSK LLLRSLMHSN ILFREFALIA MWRVPATPVG AHTLLSYLAE PLKQLSENPD
TLEDYVSENL QEFQDWNEYY SCDAKYRNWL KFQLENAEVT ELSEEENQKA VVAAKETLDS
SLSLLLRQDN PWMTFLEDHV FESEEYLFLE LHATAMLCLP SGECLRPDAT VCAALMSALY
SSVSEEVVLD RQLMVNVSIS SRDSYCIEVV LRCLAIKGDG LGPHNANDGG ILSAVAAAGF
KGSDIYGTYF SFTYDLPPFS IEIWGCELTR FQAGVTMDIS RLDAWYSSKE GSLETPATYI
VRGLCRRCCL PELVLRSMQV SVSLMESGNP PEDHDELIEL VASDETGFLS LFSRQQLQEF
MLFEREYRMS QLELQEELSS P
