NU155_ARATH
ID NU155_ARATH Reviewed; 1464 AA.
AC F4HXV6; Q9LQU6;
DT 26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Nuclear pore complex protein NUP155 {ECO:0000303|PubMed:12034489};
DE AltName: Full=Nucleoporin 155 {ECO:0000312|EMBL:AEE29235.1};
GN Name=NUP155 {ECO:0000303|PubMed:12034489};
GN OrderedLocusNames=At1g14850 {ECO:0000312|Araport:AT1G14850};
GN ORFNames=F10B6.25 {ECO:0000312|EMBL:AAF79236.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP IDENTIFICATION, AND FUNCTION.
RX PubMed=12034489; DOI=10.1016/s0378-1119(02)00470-5;
RA Zhang X., Yang H., Yu J., Chen C., Zhang G., Bao J., Du Y., Kibukawa M.,
RA Li Z., Wang J., Hu S., Dong W., Wang J., Gregersen N., Niebuhr E.,
RA Bolund L.;
RT "Genomic organization, transcript variants and comparative analysis of the
RT human nucleoporin 155 (NUP155) gene.";
RL Gene 288:9-18(2002).
RN [4]
RP IDENTIFICATION IN THE NUCLEAR PORE COMPLEX BY MASS SPECTROMETRY, AND
RP NOMENCLATURE.
RX PubMed=21189294; DOI=10.1105/tpc.110.079947;
RA Tamura K., Fukao Y., Iwamoto M., Haraguchi T., Hara-Nishimura I.;
RT "Identification and characterization of nuclear pore complex components in
RT Arabidopsis thaliana.";
RL Plant Cell 22:4084-4097(2010).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- FUNCTION: Major component of the nuclear pore complex (NPC).
CC {ECO:0000305|PubMed:12034489}.
CC -!- SUBUNIT: Part of the nuclear pore complex (NPC). The NPC has an eight-
CC fold symmetrical structure comprising a central transport channel and
CC two rings, the cytoplasmic and nuclear rings, to which eight filaments
CC are attached. The cytoplasmic filaments have loose ends, while the
CC nuclear filaments are joined in a distal ring, forming a nuclear
CC basket. NPCs are highly dynamic in configuration and composition, and
CC can be devided in 3 subcomplexes, the NUP62 subcomplex, the NUP107-160
CC subcomplex and the NUP93 subcomplex, containing approximately 30
CC different nucleoporin proteins. {ECO:0000305|PubMed:21189294}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000305|PubMed:21189294}.
CC -!- SIMILARITY: Belongs to the non-repetitive/WGA-negative nucleoporin
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79236.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006917; AAF79236.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29235.1; -; Genomic_DNA.
DR RefSeq; NP_172938.2; NM_101354.3.
DR AlphaFoldDB; F4HXV6; -.
DR SMR; F4HXV6; -.
DR BioGRID; 23290; 5.
DR STRING; 3702.AT1G14850.1; -.
DR iPTMnet; F4HXV6; -.
DR PaxDb; F4HXV6; -.
DR PRIDE; F4HXV6; -.
DR ProteomicsDB; 249210; -.
DR EnsemblPlants; AT1G14850.1; AT1G14850.1; AT1G14850.
DR GeneID; 838050; -.
DR Gramene; AT1G14850.1; AT1G14850.1; AT1G14850.
DR KEGG; ath:AT1G14850; -.
DR Araport; AT1G14850; -.
DR TAIR; locus:2006802; AT1G14850.
DR eggNOG; KOG1900; Eukaryota.
DR HOGENOM; CLU_000429_1_0_1; -.
DR InParanoid; F4HXV6; -.
DR OMA; EYYSRMI; -.
DR OrthoDB; 140051at2759; -.
DR PRO; PR:F4HXV6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HXV6; baseline and differential.
DR Genevisible; F4HXV6; AT.
DR GO; GO:0005643; C:nuclear pore; ISS:TAIR.
DR GO; GO:0044611; C:nuclear pore inner ring; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0006913; P:nucleocytoplasmic transport; ISS:TAIR.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR GO; GO:0036228; P:protein localization to nuclear inner membrane; IBA:GO_Central.
DR GO; GO:0006405; P:RNA export from nucleus; IBA:GO_Central.
DR GO; GO:0000972; P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR Gene3D; 1.20.120.1880; -; 1.
DR Gene3D; 1.25.40.440; -; 1.
DR Gene3D; 1.25.40.450; -; 1.
DR InterPro; IPR014908; Nucleoporin_Nup133/Nup155_N.
DR InterPro; IPR004870; Nucleoporin_Nup155.
DR InterPro; IPR042533; Nucleoporin_Nup155_C_1.
DR InterPro; IPR042537; Nucleoporin_Nup155_C_2.
DR InterPro; IPR042538; Nucleoporin_Nup155_C_3.
DR PANTHER; PTHR10350; PTHR10350; 1.
DR Pfam; PF08801; Nucleoporin_N; 1.
PE 1: Evidence at protein level;
KW Acetylation; mRNA transport; Nuclear pore complex; Nucleus;
KW Protein transport; Reference proteome; Translocation; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..1464
FT /note="Nuclear pore complex protein NUP155"
FT /id="PRO_0000431077"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 1464 AA; 160014 MW; 5916954B5DBB88CB CRC64;
MSQDDEIVMR DVTSAGICIG DRIGREAASQ LDLEEALEAS RYASHPYSTH PREWPPLIEV
GETWELPSVL IERYNTAGGE GTALCGIFPE IRRAWASVDN SLFLWRFDKR DGQCPEYSGE
EQAICAVGLA KCRPGVFVEA IQYLLVLATP VELVLVGVCC TEGPDGRDPY AEISVQPLPD
YTISSDGVTM TCVTCTNKGR IFMAGRDGHI YELLYTTGSG WNKRCRKVCL TAGVGSMISR
WVVPNVFKFG AVDPVVEMVV DNERQILYAR TEEMKLQAYV SGPNGEGPLK KVAEERNLLN
QKDLSQGNRQ SAVAGRSNKP SIVSISPLSM LESKWLHLVA ALSDGRRMYL STSSSGSGST
ISFSGFNNHR QTPNCLKVVS TRPSPPLGVG VGLGFGAASV AGRTQNDDLS MKIETAYYSV
GTLVLSDSSP PAMSSLLVVS RDSSVHSQAG SSSGPSSRSS RALREVVSSL PIEGRMLFVA
DVLPSPDTAA TIQSLYSELE YCGVEVSGES YEKACGKLWA RSDLSTQHIL PRRKIVVFTT
MGMMELVFNR PVDILRRLLE SNSPRSLLED FFTRFGVGEA AAMCLMLAAR IINFEDLISN
IVADKAAEAF EDPRIVGMPQ FDGSSGLSNT RTATGGFSMG QVVQEAEPIF SGAHEGLCLC
TSRLLFPLWE LPVMSKKTSS DTMSEDGVVI CRLSTSAMHV LESKIRSLEK FLRSRRNQRR
GLYGCVAGLG DVTGSILYGT GSELGATERN MVRNLFGAYS NGGESANKRQ RLPYSPAELA
ATEVRAMECI RQLLLRSAEA LFLLQLLSQH HVARLVQELD ANLKQALVQL TFHQLVCSEE
GDQIATRLIS AVMEYYTGSD GRGTVDDISP RLREGCPSYF KESDYKFYLA VERLERAALT
SDAEEKENVA REAFSFLSKV PGSADLQTVC KRFEDLRFYE AVVCLPLQKA QALDPAGDAF
NDQLDASIRE HALAQRKQCY EIIANALRSL ASPLASPTLD EASRSQYICQ IVHLGVQSTD
RAFREYLYKA MIELHLENEL LEYGGPDLVP FLQNAGSHSE SQVGAVSTGS SPLGHSGTQI
SSDQAKYFDL LAKYYVSKRQ HVLAAHVFLR LAERRAISLG DSPTLERRRD DLSQAVLQAK
NASNSDGLVG SAQGVSDSGL LDLLEGKLAV LQFQIKIRDK LEAIASNFES SVAMQDSDQN
GQVLDGDSSD DTNLANAANE MAMEVSSELK SVTQLYNEYA VPFELWEICL EMLYFANYSG
DADSSIIRET WARLIDQALS QGGIREACAV LKRVGSHIYP GDGVVLPLDV LCLHLERAAL
ERSERIENVR DEDIAKALLA ACKGAAEPVL NAYDRLLSNA AVVPSPNLRI RLLRSVLVVL
REWAMSVLSD RMGSSPTRSS LILGGSFALE NKAALNQGAR DKIANAANRY MTEVRRLALP
PNKTDGVYAG FKELDESLLS PFSF
