ID   NU4C_LOTJA              Reviewed;         497 AA.
AC   Q9BBP3;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=NAD(P)H-quinone oxidoreductase chain 4, chloroplastic;
DE            EC=7.1.1.-;
DE   AltName: Full=NAD(P)H dehydrogenase, chain 4;
DE   AltName: Full=NADH-plastoquinone oxidoreductase chain 4;
GN   Name=ndhD;
OS   Lotus japonicus (Lotus corniculatus var. japonicus).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; robinioid clade; Loteae; Lotus.
OX   NCBI_TaxID=34305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Miyakojima MG-20;
RX   PubMed=11214967; DOI=10.1093/dnares/7.6.323;
RA   Kato T., Kaneko T., Sato S., Nakamura Y., Tabata S.;
RT   "Complete structure of the chloroplast genome of a legume, Lotus
RT   japonicus.";
RL   DNA Res. 7:323-330(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC         H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC         Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC         H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC         Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
CC   -!- RNA EDITING: Modified_positions=1 {ECO:0000250}; Note=The initiator
CC       methionine is created by RNA editing. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the complex I subunit 4 family. {ECO:0000305}.
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DR   EMBL; AP002983; BAB33245.1; -; Genomic_DNA.
DR   RefSeq; NP_084845.1; NC_002694.1.
DR   AlphaFoldDB; Q9BBP3; -.
DR   SMR; Q9BBP3; -.
DR   GeneID; 802869; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   HAMAP; MF_00491; NDH1_NuoM; 1.
DR   InterPro; IPR022997; NADH_Q_OxRdtase_chain4.
DR   InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR   InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR   InterPro; IPR001750; ND/Mrp_mem.
DR   PANTHER; PTHR43507; PTHR43507; 1.
DR   Pfam; PF00361; Proton_antipo_M; 1.
DR   PRINTS; PR01437; NUOXDRDTASE4.
DR   TIGRFAMs; TIGR01972; NDH_I_M; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; NAD; NADP; Plastid; Plastoquinone; Quinone;
KW   RNA editing; Thylakoid; Translocase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..497
FT                   /note="NAD(P)H-quinone oxidoreductase chain 4,
FT                   chloroplastic"
FT                   /id="PRO_0000118016"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        463..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   497 AA;  55953 MW;  AAB76A635817B87C CRC64;
     MNYFPWLTLV VILPIAGGSL IFLFPHRGNK VIRWYTVCIC LIDLLLTTYA FCYHFQLDDP
     LIQLTESYKW INFFDFYWRF GIDGLSIGPI LLTGFITTLA TLAAQPITRE CKLFYFLMLA
     MYSGQIGPFS SRDILLFFIM WELELIPVYL LLAMWGGKKR LYSATKFILY TAGSSVFLLM
     ATLGIGLYGS NEPTLNFETL NNQSYPLALE IIVYIGFLIA FAVKSPIIPL HTWLPDTHGE
     AHYSTCMLLA GILLKMGAYG LVRINMELFS HAHSIFCPWL MILGSIQIIY AASASLGQRN
     LKKRIAYSSV SHMGFLIIGI GSISDTGLNG AILQIISHGF IGAALFFLSG TSYDRLRLLY
     LDEMGGMALP MPKIFTVFTI LSMASLALPG MSGFFAELIV FWGIITSQKY FLIMKILITF
     VTAIGMILTP IYSLSILRQM FYGYKFFNTP NSYFFDSGPR ELFISISILI PIIGIGIYPD
     FIFSFSVDKV EAVLSHF