NU4C_MAIZE
ID NU4C_MAIZE Reviewed; 500 AA.
AC P11647;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=NAD(P)H-quinone oxidoreductase chain 4, chloroplastic;
DE EC=7.1.1.-;
DE AltName: Full=NAD(P)H dehydrogenase, chain 4;
DE AltName: Full=NADH-plastoquinone oxidoreductase chain 4;
GN Name=ndhD; Synonyms=ndh4;
OS Zea mays (Maize).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX AGRICOLA=IND92000048; DOI=10.1007/BF00027381;
RA Schantz R., Bogorad L.;
RT "Maize chloroplast genes ndhD, ndhE and psaC. Sequences, transcripts and
RT transcript pools.";
RL Plant Mol. Biol. 11:239-247(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73;
RX PubMed=7666415; DOI=10.1006/jmbi.1995.0460;
RA Maier R.M., Neckermann K., Igloi G.L., Koessel H.;
RT "Complete sequence of the maize chloroplast genome: gene content, hotspots
RT of divergence and fine tuning of genetic information by transcript
RT editing.";
RL J. Mol. Biol. 251:614-628(1995).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA31558.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; X13159; CAA31558.1; ALT_INIT; Genomic_DNA.
DR EMBL; X86563; CAA60349.1; -; Genomic_DNA.
DR PIR; JU0009; QXZM4.
DR RefSeq; NP_043087.1; NC_001666.2.
DR AlphaFoldDB; P11647; -.
DR SMR; P11647; -.
DR STRING; 4577.GRMZM5G800096_P01; -.
DR PaxDb; P11647; -.
DR PRIDE; P11647; -.
DR GeneID; 845183; -.
DR KEGG; zma:845183; -.
DR MaizeGDB; 69251; -.
DR eggNOG; KOG4845; Eukaryota.
DR OrthoDB; 996580at2759; -.
DR Proteomes; UP000007305; Chloroplast.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048039; F:ubiquinone binding; IBA:GO_Central.
DR GO; GO:0009060; P:aerobic respiration; IBA:GO_Central.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IBA:GO_Central.
DR HAMAP; MF_00491; NDH1_NuoM; 1.
DR InterPro; IPR022997; NADH_Q_OxRdtase_chain4.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR PANTHER; PTHR43507; PTHR43507; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
DR TIGRFAMs; TIGR01972; NDH_I_M; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; NAD; NADP; Plastid; Plastoquinone; Quinone;
KW Reference proteome; Thylakoid; Translocase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..500
FT /note="NAD(P)H-quinone oxidoreductase chain 4,
FT chloroplastic"
FT /id="PRO_0000118017"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 462..482
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 209
FT /note="W -> L (in Ref. 1; CAA31558)"
FT /evidence="ECO:0000305"
FT CONFLICT 472
FT /note="V -> L (in Ref. 1; CAA31558)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 500 AA; 56515 MW; 2FBAB26141993793 CRC64;
MSYFPWLTIL VVLPIFAGSL IFFLPHKGNK IVRWYTIAIC LLEFLLMTYA FCYHFQLEDP
LIQLKEDSKW IDVFDFHWRL GIDPLSLGSI LLTGFITTLA TLAAWPVTRN SQLFYFLMLA
MYSGQIGLFS SRDLLLFFIM WELELIPVYL LLSMWGGKRR LYSATKFILY TAGGSIFFLI
GVLGMGLYGS NEPGLDLERL INQSYPTTWE ILLYFGFLIA YAVKLPIIPL HTWLPYTHGE
AHYSTCMLLA GILLKMGAYG LIRVNMELLP HAHYLFSPWL VIIGAVQIIY AASTSLGQRN
FKKRIAYSSV SHMGFIIIGI GSITNIGLNG AILQILSHGF IGATLFFLAG TACDRMRLVY
LEELGGISIP MPKIFTMFSS FSMASLALPG MSGFVAELVV FFGLITSPKF MLMPKMLITF
VMAIGMILTP IYLLSMLRQM FYGYKLFHVP NKNFVDSGPR ELFLLICIFL PVIGIGIYPD
LVLSLSVDRV EVLLSNYYTK
