NU4C_OENEH
ID NU4C_OENEH Reviewed; 507 AA.
AC P58419;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 2.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=NAD(P)H-quinone oxidoreductase chain 4, chloroplastic;
DE EC=7.1.1.-;
DE AltName: Full=NAD(P)H dehydrogenase, chain 4;
DE AltName: Full=NADH-plastoquinone oxidoreductase chain 4;
GN Name=ndhD;
OS Oenothera elata subsp. hookeri (Hooker's evening primrose) (Oenothera
OS hookeri).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Onagraceae; Onagroideae; Onagreae; Oenothera.
OX NCBI_TaxID=85636;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Johansen;
RX PubMed=10852478; DOI=10.1007/pl00008686;
RA Hupfer H., Swiatek M., Hornung S., Herrmann R.G., Maier R.M., Chiu W.-L.,
RA Sears B.;
RT "Complete nucleotide sequence of the Oenothera elata plastid chromosome,
RT representing plastome I of the five distinguishable Euoenothera
RT plastomes.";
RL Mol. Gen. Genet. 263:581-585(2000).
RN [2]
RP SEQUENCE REVISION TO 230; 482 AND 500.
RX PubMed=18299283; DOI=10.1093/nar/gkn081;
RA Greiner S., Wang X., Rauwolf U., Silber M.V., Mayer K., Meurer J.,
RA Haberer G., Herrmann R.G.;
RT "The complete nucleotide sequences of the five genetically distinct plastid
RT genomes of Oenothera, subsection Oenothera: I. Sequence evaluation and
RT plastome evolution.";
RL Nucleic Acids Res. 36:2366-2378(2008).
RN [3]
RP RNA EDITING OF INITIATOR CODON.
RC STRAIN=cv. Johansen;
RA Hupfer H., Maier R.M., Herrmann R.G.;
RL Unpublished observations (NOV-2001).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
CC -!- RNA EDITING: Modified_positions=1 {ECO:0000269|Ref.3}; Note=The
CC initiator methionine is created by RNA editing.;
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family. {ECO:0000305}.
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DR EMBL; AJ271079; CAB67220.3; -; Genomic_DNA.
DR RefSeq; YP_001649207.1; NC_002693.2.
DR AlphaFoldDB; P58419; -.
DR SMR; P58419; -.
DR GeneID; 802777; -.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR HAMAP; MF_00491; NDH1_NuoM; 1.
DR InterPro; IPR022997; NADH_Q_OxRdtase_chain4.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR PANTHER; PTHR43507; PTHR43507; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
DR TIGRFAMs; TIGR01972; NDH_I_M; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; NAD; NADP; Plastid; Plastoquinone; Quinone;
KW RNA editing; Thylakoid; Translocase; Transmembrane; Transmembrane helix.
FT CHAIN 1..507
FT /note="NAD(P)H-quinone oxidoreductase chain 4,
FT chloroplastic"
FT /id="PRO_0000118022"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 416..436
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 462..482
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 483..503
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 507 AA; 56837 MW; CF9B70D5DA370767 CRC64;
MNSFPWLTII VVFPILTGSL IFLLPHRGNK VMKWYTLCIC ILELLLTTYT FCYHFQLDDP
LTQLTENYKW IHFFDFYWRL GIDGLSIGPI LLTGFITTLA TLAAWPVTRD AQLFHFLMLA
MYSGQIGSFS SRDLLLFFLM WEFELIPVYL LLSMWGGKKR LYSATKFILY TAGGSIFLLI
GVLGIGLYGS NEPTLNFETL ANQSYPVALE VIFYVGFLIA FAVKLPIIPF HTWLPDTHGE
AHYSTCMLLA GILLKMGAYG LVRINMELLP HAHCLFSPGL IIVGAIQIIY AASTSPGQLN
LKKRIAYSSI SHMGFIIIGI GSLSDTGLNG AILQIISHGF IGAALFFLAG TSYDRIRLLY
LDEMGGMAIP LPKLFTMLSI LSMASLALPG LSGFVAELLV FFGIITSQKY LLMPKILIAF
LMAIGMILTP IYSLSMLRQM FYGYKLFNVP NYYFFDSGPR ELFVSISLLL PIIGIGIYPD
FVLSLSVEKV EAIISHFFFS IVFKKKE
