ID   NU4LM_MONPE             Reviewed;          87 AA.
AC   Q6U7Y2;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 4L;
DE            EC=7.1.1.2;
DE   AltName: Full=NADH dehydrogenase subunit 4L;
GN   Name=ND4L; Synonyms=NAD4L;
OS   Moniliophthora perniciosa (strain FA553 / isolate CP02) (Witches'-broom
OS   disease fungus) (Marasmius perniciosus).
OG   Mitochondrion.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiaceae; Moniliophthora.
OX   NCBI_TaxID=554373;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FA553 / isolate CP02;
RX   PubMed=18786820; DOI=10.1016/j.mycres.2008.04.014;
RA   Formighieri E.F., Tiburcio R.A., Armas E.D., Medrano F.J., Shimo H.,
RA   Carels N., Goes-Neto A., Cotomacci C., Carazzolle M.F., Sardinha-Pinto N.,
RA   Thomazella D.P.T., Rincones J., Digiampietri L., Carraro D.M.,
RA   Azeredo-Espin A.M., Reis S.F., Deckmann A.C., Gramacho K., Goncalves M.S.,
RA   Moura Neto J.P., Barbosa L.V., Meinhardt L.W., Cascardo J.C.M.,
RA   Pereira G.A.G.;
RT   "The mitochondrial genome of the phytopathogenic basidiomycete
RT   Moniliophthora perniciosa is 109 kb in size and contains a stable
RT   integrated plasmid.";
RL   Mycol. Res. 112:1136-1152(2008).
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain
CC       NADH dehydrogenase (Complex I) which catalyzes electron transfer from
CC       NADH through the respiratory chain, using ubiquinone as an electron
CC       acceptor. {ECO:0000250|UniProtKB:P03902}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) +
CC         NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA-
CC         COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2;
CC   -!- SUBUNIT: Core subunit of respiratory chain NADH dehydrogenase (Complex
CC       I) which is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:P03902}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P03902}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 4L family. {ECO:0000305}.
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DR   EMBL; AY376688; AAQ74269.1; -; Genomic_DNA.
DR   RefSeq; YP_025850.1; NC_005927.1.
DR   AlphaFoldDB; Q6U7Y2; -.
DR   SMR; Q6U7Y2; -.
DR   STRING; 554373.Q6U7Y2; -.
DR   GeneID; 2846938; -.
DR   InParanoid; Q6U7Y2; -.
DR   PhylomeDB; Q6U7Y2; -.
DR   Proteomes; UP000000741; Mitochondrion.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR   InterPro; IPR001133; NADH_UbQ_OxRdtase_chain4L/K.
DR   InterPro; IPR039428; NUOK/Mnh_C1-like.
DR   PANTHER; PTHR11434; PTHR11434; 1.
DR   Pfam; PF00420; Oxidored_q2; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   NAD; Reference proteome; Respiratory chain; Translocase; Transmembrane;
KW   Transmembrane helix; Transport; Ubiquinone.
FT   CHAIN           1..87
FT                   /note="NADH-ubiquinone oxidoreductase chain 4L"
FT                   /id="PRO_0000118409"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   87 AA;  9658 MW;  A9F1D90452A8B450 CRC64;
     MNLSIFLFLI GILGFILNRK NIILMIIAIE IMLLAVTLLV LISSFGFDDN VGQTFSLYII
     SIAGAESVIG LSILVAFYRL FLVLNYL