NU5C_PSINU
ID NU5C_PSINU Reviewed; 740 AA.
AC Q8W8H5;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic;
DE EC=7.1.1.-;
DE AltName: Full=NAD(P)H dehydrogenase subunit 5;
DE AltName: Full=NADH-plastoquinone oxidoreductase subunit 5;
GN Name=ndhF;
OS Psilotum nudum (Whisk fern) (Lycopodium nudum).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Polypodiopsida; Ophioglossidae; Psilotales; Psilotaceae; Psilotum.
OX NCBI_TaxID=3240;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Kingyoku;
RX PubMed=15240838; DOI=10.1093/molbev/msh203;
RA Nishiyama T., Wolf P.G., Kugita M., Sinclair R.B., Sugita M., Sugiura C.,
RA Wakasugi T., Yamada K., Yoshinaga K., Yamaguchi K., Ueda K., Hasebe M.;
RT "Chloroplast phylogeny indicates that bryophytes are monophyletic.";
RL Mol. Biol. Evol. 21:1813-1819(2004).
CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN
CC and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain
CC and possibly in a chloroplast respiratory chain. The immediate electron
CC acceptor for the enzyme in this species is believed to be
CC plastoquinone. Couples the redox reaction to proton translocation, and
CC thus conserves the redox energy in a proton gradient (By similarity).
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of which
CC are encoded in the nucleus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I subunit 5 family. {ECO:0000305}.
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DR EMBL; AP004638; BAB84270.1; -; Genomic_DNA.
DR EMBL; AP004638; BAB84286.1; -; Genomic_DNA.
DR RefSeq; NP_569681.1; NC_003386.1.
DR RefSeq; NP_569697.1; NC_003386.1.
DR AlphaFoldDB; Q8W8H5; -.
DR SMR; Q8W8H5; -.
DR GeneID; 2545120; -.
DR GeneID; 2545121; -.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR002128; NADH_UbQ_OxRdtase_chlpt_su5_C.
DR InterPro; IPR018393; NADHpl_OxRdtase_5_subgr.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR003945; NU5C-like.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR42829; PTHR42829; 1.
DR Pfam; PF01010; Proton_antipo_C; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR TIGRFAMs; TIGR01974; NDH_I_L; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; NAD; NADP; Plastid; Plastoquinone; Quinone;
KW Thylakoid; Translocase; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..740
FT /note="NAD(P)H-quinone oxidoreductase subunit 5,
FT chloroplastic"
FT /id="PRO_0000360970"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 532..552
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 584..604
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 673..693
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 705..725
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 740 AA; 81112 MW; 6BD250272F6B084A CRC64;
MEPLYGYAWI IPLCPFGASV LLGLGLFCLP GATGILRRAC AIMSTLLLSV SMVISPNLFS
QQINGSPTHQ SSWSWIPHKN IPLEVGFFID PLTSIMLILV TTVGVLVMIY SDSYMSHDQG
YVRFFVYLSF FTASMLGLVL SSNLVQIYIF RELVGMCSYL LIGFWFTRPS AANACQKAFI
TNRVGDFGLL LGILGIYWIT GSFEIHDLSE RFDELIANNG INLLLANTCA ILLFLGPVAK
SAQFPLHVWL PDAMEGPTPI SALIHAATMV AAGVFLVARM FHFFKALPLT MSFISWIGAI
TALMGATLAL AQKDLKRGLA YSTMSQLGYM MLAMGIGSYR AALFHLITHA YSKALLFLGS
GSVIHSMEPI VGYSPDKCQN MALMGGLRAY MPITGITFLF GTLSLCGIPP FACFWSKDKI
LADSWSYSPI LGGIAWFTAG LTAFYMSRIY LLTFEGDFRA NASIGTVTDA PLPSRHSLYV
GNLTKDSGNV IHTVPQFVQD EAVPNKSFGN VRNPSSSSPP KRNLRFPEES DFLMILPLVL
LAIPTLFIGS LGAPFLREGF SSNLPFNWLD PILVYSIKTN SEDWLDLVLD SVPSIAVASL
GILISLTLYG PTSSLPRDLR EGIDPEATGT LGSLLDSIYN WSYYRGYIDG LYNLTFVRGM
RTLAKTIYSF DRWIVDGIVN GIGISGLFGG VGMRYGGGRV SSHLIGLITG LVSLLILLIR
NAGFFSNISH EYYPLFFFER
