NU6C_ACOAM
ID NU6C_ACOAM Reviewed; 177 AA.
AC A9LYF3; A9QAR3;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic;
DE EC=7.1.1.-;
DE AltName: Full=NAD(P)H dehydrogenase subunit 6;
DE AltName: Full=NADH-plastoquinone oxidoreductase subunit 6;
GN Name=ndhG;
OS Acorus americanus (Sweetflag) (Acorus calamus var. americanus).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Acoraceae; Acorus.
OX NCBI_TaxID=263995;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=18048330; DOI=10.1073/pnas.0709121104;
RA Jansen R.K., Cai Z., Raubeson L.A., Daniell H., dePamphilis C.W.,
RA Leebens-Mack J., Muller K.F., Guisinger-Bellian M., Haberle R.C.,
RA Hansen A.K., Chumley T.W., Lee S.B., Peery R., McNeal J.R., Kuehl J.V.,
RA Boore J.L.;
RT "Analysis of 81 genes from 64 plastid genomes resolves relationships in
RT angiosperms and identifies genome-scale evolutionary patterns.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:19369-19374(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Peery R.M., Chumley T.W., Kuehl J.V., Boore J.L., Raubeson L.A.;
RT "The complete chloroplast genome of Acorus americanus.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN
CC and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain
CC and possibly in a chloroplast respiratory chain. The immediate electron
CC acceptor for the enzyme in this species is believed to be
CC plastoquinone. Couples the redox reaction to proton translocation, and
CC thus conserves the redox energy in a proton gradient (By similarity).
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of which
CC are encoded in the nucleus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I subunit 6 family. {ECO:0000305}.
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DR EMBL; EU016715; ABU85156.1; -; Genomic_DNA.
DR EMBL; EU273602; ABX38796.1; -; Genomic_DNA.
DR RefSeq; YP_001586234.1; NC_010093.1.
DR AlphaFoldDB; A9LYF3; -.
DR SMR; A9LYF3; -.
DR GeneID; 5777758; -.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1200; -; 1.
DR InterPro; IPR001457; NADH_UbQ/plastoQ_OxRdtase_su6.
DR InterPro; IPR042106; Nuo/plastoQ_OxRdtase_6_NuoJ.
DR Pfam; PF00499; Oxidored_q3; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; NAD; NADP; Plastid; Plastoquinone; Quinone;
KW Thylakoid; Translocase; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..177
FT /note="NAD(P)H-quinone oxidoreductase subunit 6,
FT chloroplastic"
FT /id="PRO_0000360221"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 177 AA; 19258 MW; E26FC9A2BC55C515 CRC64;
MDLPGPIHDV LLVFLGSGLI LGGLGVVLLT NPIYSAFSLG LVLVCISLFY ILSNSYFVAA
AQLLIYVGAV NVLIIFAVMF MNGSDYSNDF YLWTVGDGVT SLVCTSILFS LITTILDTSW
YGIIWNTGSN QIVEQDLTSN VQQIGIHLST DFYLPFELVS IILLVALIGA ITMARQY
