ID   NU6M_ALBCA              Reviewed;         155 AA.
AC   P48922;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 6;
DE            EC=7.1.1.2;
DE   AltName: Full=NADH dehydrogenase subunit 6;
GN   Name=ND6;
OS   Albinaria caerulea (Land snail).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Eupulmonata; Stylommatophora;
OC   Helicina; Clausilioidea; Clausiliidae; Alopiinae; Albinaria.
OX   NCBI_TaxID=42349;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7498775; DOI=10.1093/genetics/140.4.1353;
RA   Hatzoglou E., Rodakis G.C., Lecanidou R.;
RT   "Complete sequence and gene organization of the mitochondrial genome of the
RT   land snail Albinaria coerulea.";
RL   Genetics 140:1353-1366(1995).
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain
CC       NADH dehydrogenase (Complex I) that is believed to belong to the
CC       minimal assembly required for catalysis. Complex I functions in the
CC       transfer of electrons from NADH to the respiratory chain. The immediate
CC       electron acceptor for the enzyme is believed to be ubiquinone (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) +
CC         NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA-
CC         COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2;
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 6 family. {ECO:0000305}.
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DR   EMBL; X83390; CAA58308.1; -; Genomic_DNA.
DR   PIR; S59155; S59155.
DR   RefSeq; NP_007341.1; NC_001761.1.
DR   AlphaFoldDB; P48922; -.
DR   GeneID; 808001; -.
DR   CTD; 4541; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; NAD; Respiratory chain;
KW   Translocase; Transmembrane; Transmembrane helix; Transport; Ubiquinone.
FT   CHAIN           1..155
FT                   /note="NADH-ubiquinone oxidoreductase chain 6"
FT                   /id="PRO_0000118233"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   155 AA;  17496 MW;  807B676CFE7EA991 CRC64;
     MMSLTFMAGL IFPVFMMLKG INPMSLLLAL LTLSLCAVLW LGSFMSSWYA YILFIVYIGG
     ILVLFIYVCM ISSNYIASQH MYKSLLYAWG AVMLMSLTME TDTFIILGSN MMYTSVNIPM
     TILIFLSIYL LIVFFAVVNL MVNMTSILMV ESSQV