ID   NU6M_ALBTU              Reviewed;          96 AA.
AC   Q08084;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 6;
DE            EC=7.1.1.2;
DE   AltName: Full=NADH dehydrogenase subunit 6;
DE   Flags: Fragment;
GN   Name=ND6;
OS   Albinaria turrita (Door snail) (Clausilia turrita).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Eupulmonata; Stylommatophora;
OC   Helicina; Clausilioidea; Clausiliidae; Alopiinae; Albinaria.
OX   NCBI_TaxID=27820;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8007005; DOI=10.1007/bf00163154;
RA   Lecanidou R., Douris V., Rodakis G.C.;
RT   "Novel features of metazoan mtDNA revealed from sequence analysis of three
RT   mitochondrial DNA segments of the land snail Albinaria turrita (Gastropoda:
RT   Clausiliidae).";
RL   J. Mol. Evol. 38:369-382(1994).
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain
CC       NADH dehydrogenase (Complex I) that is believed to belong to the
CC       minimal assembly required for catalysis. Complex I functions in the
CC       transfer of electrons from NADH to the respiratory chain. The immediate
CC       electron acceptor for the enzyme is believed to be ubiquinone (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) +
CC         NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA-
CC         COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2;
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the complex I subunit 6 family. {ECO:0000305}.
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DR   EMBL; X71394; CAA50516.1; -; Genomic_DNA.
DR   PIR; S33145; S33145.
DR   AlphaFoldDB; Q08084; -.
DR   SMR; Q08084; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; NAD; Respiratory chain;
KW   Translocase; Transmembrane; Transmembrane helix; Transport; Ubiquinone.
FT   CHAIN           1..>96
FT                   /note="NADH-ubiquinone oxidoreductase chain 6"
FT                   /id="PRO_0000118234"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   NON_TER         96
SQ   SEQUENCE   96 AA;  10896 MW;  A1732AACC4FADA4F CRC64;
     MMSLSFMLGL IFPVFFMFTL ANPMSLLLLL LIMSLCAVLW LGSIMSSWFA YILFIVYIGG
     ILVLFIYVCM ISSNYITGLY KYKTLLYVGM VVALMS