位置:首页 > 蛋白库 > NUCS_COREF
NUCS_COREF
ID   NUCS_COREF              Reviewed;         230 AA.
AC   Q8FQ17;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2003, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Endonuclease NucS {ECO:0000255|HAMAP-Rule:MF_00722};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00722};
GN   Name=nucS {ECO:0000255|HAMAP-Rule:MF_00722}; OrderedLocusNames=CE1318;
OS   Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS   / NBRC 100395).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196164;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX   PubMed=12840036; DOI=10.1101/gr.1285603;
RA   Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA   Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT   "Comparative complete genome sequence analysis of the amino acid
RT   replacements responsible for the thermostability of Corynebacterium
RT   efficiens.";
RL   Genome Res. 13:1572-1579(2003).
CC   -!- FUNCTION: Cleaves both 3' and 5' ssDNA extremities of branched DNA
CC       structures. {ECO:0000255|HAMAP-Rule:MF_00722}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00722}.
CC   -!- SIMILARITY: Belongs to the NucS endonuclease family.
CC       {ECO:0000255|HAMAP-Rule:MF_00722}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC18128.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000035; BAC18128.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_035109476.1; NZ_GG700686.1.
DR   AlphaFoldDB; Q8FQ17; -.
DR   SMR; Q8FQ17; -.
DR   STRING; 196164.23493157; -.
DR   EnsemblBacteria; BAC18128; BAC18128; BAC18128.
DR   KEGG; cef:CE1318; -.
DR   eggNOG; COG1637; Bacteria.
DR   HOGENOM; CLU_069350_0_0_11; -.
DR   OrthoDB; 1002946at2; -.
DR   Proteomes; UP000001409; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000014; F:single-stranded DNA endodeoxyribonuclease activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1350.10; -; 1.
DR   HAMAP; MF_00722; NucS; 1.
DR   InterPro; IPR002793; Endonuclease_NucS.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR   PANTHER; PTHR38814; PTHR38814; 1.
DR   Pfam; PF01939; NucS; 1.
DR   SUPFAM; SSF52980; SSF52980; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Endonuclease; Hydrolase; Nuclease;
KW   Reference proteome.
FT   CHAIN           1..230
FT                   /note="Endonuclease NucS"
FT                   /id="PRO_0000155681"
SQ   SEQUENCE   230 AA;  25788 MW;  C3BA2EBEB877E74D CRC64;
     MRLVIARCSV DYIGRLEAHL PMADRLLMVK ADGSVSIHAD DRAYKPLNWM TPPCTLTETP
     ITDEDGEEVG VHLWVVENKK GEQLRITVEK IHSELSHDLG VDPGLVKDGV EDHLQELLAE
     HITTLGEGYT LVRREYPTAI GPVDILCRDA DGQTVAVEIK RRGNIDGVEQ LSRYLELLNR
     DELLKPVQGV FAAQEIKPQA RTLAEDRGIR CVTLDYQTLR GIESNELTLF
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024