NUCS_SULIY
ID NUCS_SULIY Reviewed; 237 AA.
AC C3N7V1;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Endonuclease NucS {ECO:0000255|HAMAP-Rule:MF_00722};
DE EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00722};
GN Name=nucS {ECO:0000255|HAMAP-Rule:MF_00722}; OrderedLocusNames=YG5714_0025;
OS Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=439386;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y.G.57.14 / Yellowstone #1;
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- FUNCTION: Cleaves both 3' and 5' ssDNA extremities of branched DNA
CC structures. {ECO:0000255|HAMAP-Rule:MF_00722}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00722}.
CC -!- SIMILARITY: Belongs to the NucS endonuclease family.
CC {ECO:0000255|HAMAP-Rule:MF_00722}.
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DR EMBL; CP001403; ACP44319.1; -; Genomic_DNA.
DR RefSeq; WP_012710204.1; NC_012622.1.
DR AlphaFoldDB; C3N7V1; -.
DR SMR; C3N7V1; -.
DR EnsemblBacteria; ACP44319; ACP44319; YG5714_0025.
DR GeneID; 7812085; -.
DR GeneID; 7939724; -.
DR GeneID; 8759864; -.
DR KEGG; siy:YG5714_0025; -.
DR HOGENOM; CLU_069350_1_0_2; -.
DR OMA; RCSVDYA; -.
DR Proteomes; UP000002308; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000014; F:single-stranded DNA endodeoxyribonuclease activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1350.10; -; 1.
DR HAMAP; MF_00722; NucS; 1.
DR InterPro; IPR002793; Endonuclease_NucS.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR011856; tRNA_endonuc-like_dom_sf.
DR PANTHER; PTHR38814; PTHR38814; 1.
DR Pfam; PF01939; NucS; 1.
DR SUPFAM; SSF52980; SSF52980; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Endonuclease; Hydrolase; Nuclease.
FT CHAIN 1..237
FT /note="Endonuclease NucS"
FT /id="PRO_1000212721"
SQ SEQUENCE 237 AA; 27401 MW; EC53D749733EDB84 CRC64;
MYSVLLNPSN TEIYSFLTER IYRELVVIFA TCKVNYKGRA ESVASESPRL IILKPDGTVI
IHESVKREPL NWQPPGTKIE IMNDYPLKIV AQRKRPKEVI EIDLKEVFYI TSAEVKDGDF
VIKGREIDIV NTIIQNPSMI EEGFVPLTRE YNTPYGKIDL VGLDKKGNFV IIEVKRSKAQ
LSAVSQLYRY YLHIRETKED KVRGILVAPD LTTHARELLQ KLGLEFIRYD IQKYSSY