ID   NUDC_EMENI              Reviewed;         198 AA.
AC   P17624; C8VF54; Q5B2P9;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Nuclear movement protein nudC;
DE   AltName: Full=Nuclear distribution protein C;
GN   Name=nudC; ORFNames=AN5181;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2199460; DOI=10.1083/jcb.111.2.543;
RA   Osmani A.H., Osmani S.A., Morris N.R.;
RT   "The molecular cloning and identification of a gene product specifically
RT   required for nuclear movement in Aspergillus nidulans.";
RL   J. Cell Biol. 111:543-551(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Required for nuclear movement. May interact between
CC       microtubules and nuclei and/or may be involved in the generation of
CC       force used to move nuclei during interphase.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the nudC family. {ECO:0000305}.
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DR   EMBL; X52565; CAA36799.1; -; Genomic_DNA.
DR   EMBL; AACD01000089; EAA62362.1; -; Genomic_DNA.
DR   EMBL; BN001305; CBF81029.1; -; Genomic_DNA.
DR   PIR; A35851; A35851.
DR   RefSeq; XP_662785.1; XM_657693.1.
DR   AlphaFoldDB; P17624; -.
DR   SMR; P17624; -.
DR   STRING; 162425.CADANIAP00003176; -.
DR   PRIDE; P17624; -.
DR   EnsemblFungi; CBF81029; CBF81029; ANIA_05181.
DR   EnsemblFungi; EAA62362; EAA62362; AN5181.2.
DR   GeneID; 2871469; -.
DR   KEGG; ani:AN5181.2; -.
DR   VEuPathDB; FungiDB:AN5181; -.
DR   eggNOG; KOG2265; Eukaryota.
DR   HOGENOM; CLU_047332_2_0_1; -.
DR   InParanoid; P17624; -.
DR   OMA; WTLETTP; -.
DR   OrthoDB; 1474731at2759; -.
DR   Proteomes; UP000000560; Chromosome V.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0031505; P:fungal-type cell wall organization; IMP:AspGD.
DR   GO; GO:0000741; P:karyogamy; IEA:UniProtKB-KW.
DR   GO; GO:0030473; P:nuclear migration along microtubule; IMP:AspGD.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR007052; CS_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR037898; NudC_fam.
DR   PANTHER; PTHR12356; PTHR12356; 1.
DR   Pfam; PF04969; CS; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS51203; CS; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Karyogamy; Microtubule;
KW   Mitosis; Phosphoprotein; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Nuclear movement protein nudC"
FT                   /id="PRO_0000057989"
FT   DOMAIN          29..125
FT                   /note="CS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00547"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..28
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         141
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         193
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   198 AA;  22353 MW;  C8A10174D94EB2B2 CRC64;
     MSEQEPSSAD LAAREAEEKQ RKAAEEAEQA TLPYKWTQTI RDVDVTIPVS ANLKGRDLDV
     VLKKDSIKVK VKGENGEVFI DGQFPHPIKP SESSWTLETT SKPPGKEVSI HLDKVNQMEW
     WAHVVTTAPK IDVSKITPEN SSLSDLDGET RAMVEKMMYD QRQKEMGAPT SDEQRKMDIL
     KKFQKEHPEM DFSNAKIG