ID   NUDC_SCHPO              Reviewed;         166 AA.
AC   O60166;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Nuclear movement protein nudc;
DE   AltName: Full=Nuclear distribution protein C homolog;
GN   Name=nudc; ORFNames=SPBC19F8.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for nuclear movement. May interact between
CC       microtubules and nuclei and/or may be involved in the generation of
CC       force used to move nuclei during interphase (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the nudC family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA19122.1; -; Genomic_DNA.
DR   PIR; T39825; T39825.
DR   RefSeq; NP_596344.1; NM_001022264.2.
DR   AlphaFoldDB; O60166; -.
DR   SMR; O60166; -.
DR   BioGRID; 277259; 30.
DR   STRING; 4896.SPBC19F8.02.1; -.
DR   iPTMnet; O60166; -.
DR   MaxQB; O60166; -.
DR   PaxDb; O60166; -.
DR   PRIDE; O60166; -.
DR   EnsemblFungi; SPBC19F8.02.1; SPBC19F8.02.1:pep; SPBC19F8.02.
DR   GeneID; 2540736; -.
DR   KEGG; spo:SPBC19F8.02; -.
DR   PomBase; SPBC19F8.02; -.
DR   VEuPathDB; FungiDB:SPBC19F8.02; -.
DR   eggNOG; KOG2265; Eukaryota.
DR   HOGENOM; CLU_047332_2_0_1; -.
DR   InParanoid; O60166; -.
DR   OMA; WTLETTP; -.
DR   PhylomeDB; O60166; -.
DR   Reactome; R-SPO-9648025; EML4 and NUDC in mitotic spindle formation.
DR   PRO; PR:O60166; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; ISS:PomBase.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; ISS:PomBase.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR007052; CS_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR037898; NudC_fam.
DR   PANTHER; PTHR12356; PTHR12356; 1.
DR   Pfam; PF04969; CS; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS51203; CS; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Microtubule; Mitosis;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..166
FT                   /note="Nuclear movement protein nudc"
FT                   /id="PRO_0000310342"
FT   DOMAIN          6..97
FT                   /note="CS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00547"
SQ   SEQUENCE   166 AA;  19443 MW;  6AE6D74B11DCCB36 CRC64;
     MHQVKLEEAE YEWDQTIADV DIVIHVPKGT RAKSLQVDMS NHDLKIQINV PERKVLLSGP
     LEKQINLDES TWTVEEQERL VIHLEKSNKM EWWSCVIKGH PSIDIGSIEP ENSKLSDLDE
     ETRATVEKMM LEQSQKRTDE QKRKDVLQNF MKQHPELDFS NVRDQI