ID   NUG2_ORYSI              Reviewed;         535 AA.
AC   A2XGQ1;
DT   01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Nuclear/nucleolar GTPase 2 {ECO:0000305};
GN   Name=NUG2 {ECO:0000305}; ORFNames=OsI_11581 {ECO:0000312|EMBL:EAY90011.1};
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946 {ECO:0000312|Proteomes:UP000007015};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: GTPase involved in pre-60S ribosomal subunit maturation.
CC       {ECO:0000250|UniProtKB:Q10LF7}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q10LF7}. Nucleus {ECO:0000250|UniProtKB:Q10LF7}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01058}.
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DR   EMBL; CM000128; EAY90011.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2XGQ1; -.
DR   SMR; A2XGQ1; -.
DR   STRING; 39946.A2XGQ1; -.
DR   EnsemblPlants; BGIOSGA012620-TA; BGIOSGA012620-PA; BGIOSGA012620.
DR   Gramene; BGIOSGA012620-TA; BGIOSGA012620-PA; BGIOSGA012620.
DR   HOGENOM; CLU_011106_4_2_1; -.
DR   OMA; PAPFQGR; -.
DR   Proteomes; UP000007015; Chromosome 3.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR024929; NOG2.
DR   InterPro; IPR012971; NOG2_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11089:SF9; PTHR11089:SF9; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF08153; NGP1NT; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   GTP-binding; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome.
FT   CHAIN           1..535
FT                   /note="Nuclear/nucleolar GTPase 2"
FT                   /id="PRO_0000432558"
FT   DOMAIN          213..374
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          261..264
FT                   /note="G4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          290..292
FT                   /note="G5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          323..330
FT                   /note="G1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          349..353
FT                   /note="G2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          367..370
FT                   /note="G3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01058"
FT   REGION          464..495
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..494
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  60167 MW;  846C4106B639C4C8 CRC64;
     MAKKKERAVN VSGKPRHSLD VNRANDKKGA GGGAGGGGGG RSAATVRRLK MYKMRPLRDR
     GGKILKHDLQ SKELPNTRIE PDRRWFGNTR VVNQKELEFF REELQSRLSN NYNVILKERK
     LPLSLLQDHQ KQARAHLLDT EPFEHAFGPK GKRKRPKLMA LDYESLLKKA DDSQGAFEDK
     HATAKLLKEE EEDGLRDLVR HTMFEKGQSK RIWGELYKVI DSSDVVVQVL DARDPMGTRC
     YHLEKHLKEN AKHKHLVFLL NKCDLVPAWA TKGWLRTLSK DYPTLAFHAS INSSFGKGSL
     LSVLRQFARL KSDKQAISVG FVGYPNVGKS SVINTLRSKS VCKVAPIPGE TKVWQYITLT
     KRIFLIDCPG VVYQNNDSET DIVLKGVVRV TNLADASEHI GEVLRRVKKE HLKRAYKIED
     WVDDNDFLVQ LSKTTGKLLR GGEPDLTTTA KMVLHDWQRG KIPFFVPPPQ QGEDSPSETA
     EPVDKSDEEG VSSDRTAAAM KAIAGIISSQ QQMNVPCQKE FGVTNEDSEV AEQSE