ID   AROS_CHICK              Reviewed;         140 AA.
AC   Q5ZMG5;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Active regulator of SIRT1;
DE   AltName: Full=40S ribosomal protein S19-binding protein 1;
DE            Short=RPS19-binding protein 1;
DE            Short=S19BP;
GN   Name=RPS19BP1; Synonyms=AROS; ORFNames=RCJMB04_2b23;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Direct regulator of SIRT1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AROS family. {ECO:0000305}.
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DR   EMBL; AJ719419; CAG31078.1; -; mRNA.
DR   RefSeq; NP_001006239.2; NM_001006239.3.
DR   AlphaFoldDB; Q5ZMG5; -.
DR   SMR; Q5ZMG5; -.
DR   STRING; 9031.ENSGALP00000037100; -.
DR   PaxDb; Q5ZMG5; -.
DR   GeneID; 418011; -.
DR   KEGG; gga:418011; -.
DR   CTD; 91582; -.
DR   VEuPathDB; HostDB:geneid_418011; -.
DR   eggNOG; ENOG502S1CM; Eukaryota.
DR   InParanoid; Q5ZMG5; -.
DR   OrthoDB; 1513987at2759; -.
DR   PhylomeDB; Q5ZMG5; -.
DR   PRO; PR:Q5ZMG5; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005730; C:nucleolus; ISS:HGNC-UCL.
DR   GO; GO:0005654; C:nucleoplasm; ISS:HGNC-UCL.
DR   GO; GO:0019899; F:enzyme binding; IBA:GO_Central.
DR   InterPro; IPR023262; AROS.
DR   PANTHER; PTHR31454; PTHR31454; 1.
DR   Pfam; PF15684; AROS; 1.
DR   PRINTS; PR02029; ACTREGSIRT1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..140
FT                   /note="Active regulator of SIRT1"
FT                   /id="PRO_0000361538"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          95..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..123
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   140 AA;  15587 MW;  D70DB2CFB0118000 CRC64;
     MSASLIRRGL ELLEAPGQGK APPALQQGRD GTRPAGTARR RKVTAGPGKN KATIKGRVVK
     SAIEEYHKKK AVNHLKANLL YMTSGRCVAD KAVTQQVLTQ NRGRKSKDRP AEKKEKKKPE
     GTVFTEEDFR KFEREYFGIP