ARP10_MOUSE
ID ARP10_MOUSE Reviewed; 417 AA.
AC Q9QZB7; Q3TT18; Q99LU1;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 153.
DE RecName: Full=Actin-related protein 10;
DE AltName: Full=Actin-related protein 11;
GN Name=Actr10; Synonyms=Act11, Actr11, Arp10, Arp11;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=10525537; DOI=10.1083/jcb.147.2.307;
RA Eckley D.M., Gill S.R., Melkonian K.A., Bingham J.B., Goodson H.V.,
RA Heuser J.E., Schroer T.A.;
RT "Analysis of dynactin subcomplexes reveals a novel actin-related protein
RT associated with the Arp1 minifilament pointed end.";
RL J. Cell Biol. 147:307-320(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Heart, Kidney, Lung, Pancreas, Spleen, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- INTERACTION:
CC Q9QZB7; P42025: ACTR1B; Xeno; NbExp=2; IntAct=EBI-367600, EBI-367493;
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; AF190797; AAF05617.1; -; mRNA.
DR EMBL; AK161642; BAE36507.1; -; mRNA.
DR EMBL; BC002227; AAH02227.1; -; mRNA.
DR CCDS; CCDS25960.1; -.
DR RefSeq; NP_062759.2; NM_019785.2.
DR AlphaFoldDB; Q9QZB7; -.
DR SMR; Q9QZB7; -.
DR BioGRID; 207985; 14.
DR IntAct; Q9QZB7; 3.
DR MINT; Q9QZB7; -.
DR STRING; 10090.ENSMUSP00000021479; -.
DR iPTMnet; Q9QZB7; -.
DR PhosphoSitePlus; Q9QZB7; -.
DR EPD; Q9QZB7; -.
DR jPOST; Q9QZB7; -.
DR MaxQB; Q9QZB7; -.
DR PaxDb; Q9QZB7; -.
DR PeptideAtlas; Q9QZB7; -.
DR PRIDE; Q9QZB7; -.
DR ProteomicsDB; 283230; -.
DR Antibodypedia; 24149; 99 antibodies from 23 providers.
DR DNASU; 56444; -.
DR Ensembl; ENSMUST00000021479; ENSMUSP00000021479; ENSMUSG00000021076.
DR GeneID; 56444; -.
DR KEGG; mmu:56444; -.
DR UCSC; uc007nty.2; mouse.
DR CTD; 55860; -.
DR MGI; MGI:1891654; Actr10.
DR VEuPathDB; HostDB:ENSMUSG00000021076; -.
DR eggNOG; KOG0676; Eukaryota.
DR GeneTree; ENSGT00910000144250; -.
DR HOGENOM; CLU_027965_2_1_1; -.
DR InParanoid; Q9QZB7; -.
DR OMA; RVLFVHF; -.
DR OrthoDB; 964605at2759; -.
DR PhylomeDB; Q9QZB7; -.
DR TreeFam; TF315151; -.
DR Reactome; R-MMU-2132295; MHC class II antigen presentation.
DR Reactome; R-MMU-3371497; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand.
DR Reactome; R-MMU-6798695; Neutrophil degranulation.
DR Reactome; R-MMU-6807878; COPI-mediated anterograde transport.
DR Reactome; R-MMU-6811436; COPI-independent Golgi-to-ER retrograde traffic.
DR BioGRID-ORCS; 56444; 25 hits in 74 CRISPR screens.
DR ChiTaRS; Actr10; mouse.
DR PRO; PR:Q9QZB7; -.
DR Proteomes; UP000000589; Chromosome 12.
DR RNAct; Q9QZB7; protein.
DR Bgee; ENSMUSG00000021076; Expressed in seminiferous tubule of testis and 279 other tissues.
DR ExpressionAtlas; Q9QZB7; baseline and differential.
DR Genevisible; Q9QZB7; MM.
DR GO; GO:1904115; C:axon cytoplasm; IEA:GOC.
DR GO; GO:0005869; C:dynactin complex; IDA:MGI.
DR GO; GO:0007018; P:microtubule-based movement; IDA:MGI.
DR GO; GO:0098958; P:retrograde axonal transport of mitochondrion; IBA:GO_Central.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR027127; Arp10.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR PANTHER; PTHR11937:SF14; PTHR11937:SF14; 1.
DR Pfam; PF00022; Actin; 1.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
PE 1: Evidence at protein level;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..417
FT /note="Actin-related protein 10"
FT /id="PRO_0000089132"
FT CONFLICT 9
FT /note="S -> T (in Ref. 1; AAF05617)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 417 AA; 46208 MW; DFA8D7CFF0C64B0D CRC64;
MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMSK PIKVVQYNIN
TEELYSYLKE FIHILYFRHL LVNPRDRRVV VIESVLCPSH FRETLTRVLF KYFEVPSVLL
APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPILNC WGALPLGGKA LHKELETQLL
EQCTVDTGAA KGQSLPSVMG SVPEGVLEDI KVRTCFVSDL KRGLQIQAAK FNIDGNNERP
TPPPNVDYPL DGEKILHVLG SIRDSVVEIL FEQDNEEKSV ATLILDSLLQ CPIDTRKQLA
ENLVIIGGTS MLPGFLHRLL AEIRYLVEKP KYKKTLGTKN FRIHTPPAKA NCVAWLGGAV
FGALQDILGS RSISKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKAQPPLMK RAFSTEK
