ARP1_ARATH
ID ARP1_ARATH Reviewed; 261 AA.
AC Q9M1S3; Q0WLB8; Q8LFQ5;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Probable RNA-binding protein ARP1;
DE AltName: Full=ABA-regulated RNA-binding protein 1 {ECO:0000303|PubMed:23040517};
GN Name=ARP1 {ECO:0000303|PubMed:23040517};
GN OrderedLocusNames=At3g54770 {ECO:0000312|Araport:AT3G54770};
GN ORFNames=T5N23.130 {ECO:0000312|EMBL:CAB77597.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=23040517; DOI=10.1016/j.jplph.2012.09.002;
RA Jung H.J., Kim M.K., Kang H.;
RT "An ABA-regulated putative RNA-binding protein affects seed germination of
RT Arabidopsis under ABA or abiotic stress conditions.";
RL J. Plant Physiol. 170:179-184(2013).
CC -!- FUNCTION: Probable RNA-binding protein involved in the regulation of
CC abscisic acid (ABA) response during seed germination. May regulate
CC transcript levels of several germination-responsive genes under ABA.
CC {ECO:0000269|PubMed:23040517}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23040517}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences. {ECO:0000305};
CC Name=1;
CC IsoId=Q9M1S3-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in vasculature of leaves, roots and
CC siliques. {ECO:0000269|PubMed:23040517}.
CC -!- INDUCTION: Down-regulated by abscisic acid (ABA).
CC {ECO:0000269|PubMed:23040517}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but mutant seeds have decreased germination rate in
CC presence of abscisic acid (ABA) or salt, compared to wild-type.
CC {ECO:0000269|PubMed:23040517}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF02089.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AL138650; CAB77597.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79282.1; -; Genomic_DNA.
DR EMBL; AK230287; BAF02089.1; ALT_SEQ; mRNA.
DR EMBL; AY084706; AAM61280.1; -; mRNA.
DR PIR; T47636; T47636.
DR RefSeq; NP_191037.1; NM_115334.4. [Q9M1S3-1]
DR AlphaFoldDB; Q9M1S3; -.
DR SMR; Q9M1S3; -.
DR STRING; 3702.AT3G54770.1; -.
DR PaxDb; Q9M1S3; -.
DR ProteomicsDB; 246978; -. [Q9M1S3-1]
DR DNASU; 824642; -.
DR EnsemblPlants; AT3G54770.1; AT3G54770.1; AT3G54770. [Q9M1S3-1]
DR GeneID; 824642; -.
DR Gramene; AT3G54770.1; AT3G54770.1; AT3G54770. [Q9M1S3-1]
DR KEGG; ath:AT3G54770; -.
DR Araport; AT3G54770; -.
DR TAIR; locus:2102435; AT3G54770.
DR eggNOG; KOG0149; Eukaryota.
DR HOGENOM; CLU_048669_2_0_1; -.
DR InParanoid; Q9M1S3; -.
DR OrthoDB; 1579773at2759; -.
DR PhylomeDB; Q9M1S3; -.
DR PRO; PR:Q9M1S3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M1S3; baseline and differential.
DR Genevisible; Q9M1S3; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; HDA:TAIR.
DR GO; GO:0010029; P:regulation of seed germination; IMP:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Nucleus; Reference proteome; RNA-binding;
KW Stress response.
FT CHAIN 1..261
FT /note="Probable RNA-binding protein ARP1"
FT /id="PRO_0000433125"
FT DOMAIN 17..94
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 96..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 69
FT /note="K -> E (in Ref. 4; AAM61280)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 261 AA; 28857 MW; 337ED1608927B169 CRC64;
MTTSNNVNGC FGDTKLTKVF VGGLAWDTHK EAMYDHFIKY GDILEAVIIS DKLTRRSKGY
GFVTFKDAKA ATRACEDSTP IINGRRANCN LASLGGRLRK SPTMTSPQQG PKNGNRATPP
HVGNHSQWYY PSGFTNQQHQ QQNHQAVPFY GYPSAYVAPN MTFNQKVGYV GGTYMNGYYA
QMQPQPQSQP QPQYYHHHMY GGGRVMVGAA SPMVPFYTVY PYHQSQAIGF PQPSFSKPLS
FSTPPISGTV GGESIQKKAI H
