ID   ARP2_ORYSI              Reviewed;         389 AA.
AC   A2YUL5;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Actin-related protein 2;
GN   Name=ARP2; ORFNames=OsI_028008;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [2]
RP   REVIEW, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15063870; DOI=10.1016/j.tplants.2004.02.004;
RA   Kandasamy M.K., Deal R.B., McKinney E.C., Meagher R.B.;
RT   "Plant actin-related proteins.";
RL   Trends Plant Sci. 9:196-202(2004).
CC   -!- FUNCTION: Functions as ATP-binding component of the Arp2/3 complex
CC       which is involved in regulation of actin polymerization and together
CC       with an activating nucleation-promoting factor (NPF) mediates the
CC       formation of branched actin networks. Seems to contact the pointed end
CC       of the daughter actin filament. Regulates the directionality of cell
CC       expansion by regulating the actin organization, and thus the
CC       microtubules distribution and the fusion of small vacuoles (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the Arp2/3 complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP2 subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CM000133; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; CM000133; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A2YUL5; -.
DR   SMR; A2YUL5; -.
DR   STRING; 39946.A2YUL5; -.
DR   Proteomes; UP000007015; Chromosome 8.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Actin-binding; ATP-binding; Cytoplasm; Cytoskeleton; Developmental protein;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..389
FT                   /note="Actin-related protein 2"
FT                   /id="PRO_0000320524"
FT   BINDING         157..159
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         211..215
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         302..307
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   389 AA;  43852 MW;  F1C7069C76D72717 CRC64;
     MDSGNVVVCD NGTGYVKCGF AGENFPTSVF PCVVGRPLLR YEESLQEQEL TDIVVGAACA
     DLRHQLDVSY PVTNGIVQSW DDMGHIWDHA FYSELKVDPS ECKILLTDPP LNPVKNREKM
     IETMFEKYNF AGVFIQVQAV LSLYAQGLLT GLVIDSGDGV THVVPVVDGF SYPHITKRMN
     VAGRHITSYL VDLLSRRGYA MNKSADFETV REIKEKLCYL SYDYKREYQL GLETTILVKS
     YTLPDGRVIK VGTERFQAPE ALFTPELIDV EGDGMADMAF RCIQEMDIDN RMTLYQHIVL
     SGGSTMYPGL PSRLEKEMLD RYLDVVLKGN KDGLKKLRLR IEDPPRRKHM VYLGGAVLAG
     IMKDAPEFWI TRQEYQEEGL ACLRKCGQA