ARP2_PLAFA
ID ARP2_PLAFA Reviewed; 443 AA.
AC P13824; Q9TY66;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 2.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Clustered-asparagine-rich protein;
DE Short=CARP;
OS Plasmodium falciparum.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3517875; DOI=10.1073/pnas.83.8.2677;
RA Wahlgren M., Aaslund L., Franzen L., Sundvall M., Waahlin B., Berzins K.,
RA McNicol L.A., Bjoerkman A., Wigzell H., Perlmann P., Pettersson U.;
RT "A Plasmodium falciparum antigen containing clusters of asparagine
RT residues.";
RL Proc. Natl. Acad. Sci. U.S.A. 83:2677-2681(1986).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-17.
RX PubMed=8454022; DOI=10.1006/expr.1993.1016;
RA Sjolander A., Stahl S., Lovgren K., Hansson M., Cavelier L., Walles A.,
RA Helmby H., Wahlin B., Morein B., Uhlen M., Berzins K., Perlmann P.,
RA Wahlgren M.;
RT "Plasmodium falciparum: the immune response in rabbits to the clustered
RT asparagine-rich protein (CARP) after immunization in Freund's adjuvant or
RT immunostimulating complexes (ISCOMs).";
RL Exp. Parasitol. 76:134-145(1993).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA29485.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; M13021; AAA29485.1; ALT_INIT; Genomic_DNA.
DR EMBL; S56699; AAB25852.1; -; Genomic_DNA.
DR PIR; A23535; A23535.
DR AlphaFoldDB; P13824; -.
DR SMR; P13824; -.
DR VEuPathDB; PlasmoDB:PF3D7_1236100; -.
DR VEuPathDB; PlasmoDB:Pf7G8-2_000385600; -.
DR VEuPathDB; PlasmoDB:Pf7G8_120041400; -.
DR VEuPathDB; PlasmoDB:PfCD01_120040800; -.
DR VEuPathDB; PlasmoDB:PfDd2_120040900; -.
DR VEuPathDB; PlasmoDB:PfGA01_120040600; -.
DR VEuPathDB; PlasmoDB:PfGB4_120041300; -.
DR VEuPathDB; PlasmoDB:PfGN01_120041900; -.
DR VEuPathDB; PlasmoDB:PfHB3_120040700; -.
DR VEuPathDB; PlasmoDB:PfIT_120041000; -.
DR VEuPathDB; PlasmoDB:PfKE01_120040900; -.
DR VEuPathDB; PlasmoDB:PfKH01_120042300; -.
DR VEuPathDB; PlasmoDB:PfKH02_120041000; -.
DR VEuPathDB; PlasmoDB:PfML01_120041400; -.
DR VEuPathDB; PlasmoDB:PfNF135_120041100; -.
DR VEuPathDB; PlasmoDB:PfNF166_120042500; -.
DR VEuPathDB; PlasmoDB:PfNF54_120040600; -.
DR VEuPathDB; PlasmoDB:PfSD01_120040800; -.
DR VEuPathDB; PlasmoDB:PfSN01_120041400; -.
DR VEuPathDB; PlasmoDB:PfTG01_120040800; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Malaria; Repeat; RNA-binding.
FT CHAIN 1..443
FT /note="Clustered-asparagine-rich protein"
FT /id="PRO_0000081486"
FT DOMAIN 16..106
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 342..435
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 253..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 51176 MW; 7971251554567C72 CRC64;
MNNEIVNSTI DGVLNTKLHI QNIPPHITDV HLRSLLGNVG FIKDICYFNK SKKQMNNNNF
ANKKIYNTAL VTFNTHEEAL NVLKNIKNLI DTSGEERNID AKFAVPNVSI NNNNNNNNSN
TFFQKNNMNN TNFSQGSTNY GSNYNSENFQ GNNNMNNYNF YNNNSSNNNN NNQTNTQNNF
MNRNMKNKNM NNNNNNNNSN NNMMMNMNFN NNQQMNNNPM LNQNNFMLNN NNNYNNNAKN
VNDMYRDGEM SPNHLNNNNN NINNNNNNNN NNNNNNNVMF RQNNSHLAQM YQANDNSLED
VENVDGLSLW EMYKDKNNNI FYYNNLTKHA NGINLFTQTN YSSITIMKKQ NKMDLVEVTY
LFSTYLVNGQ TLIYSNISVV LVILYHQKFK ETVLGRNSGF GFVSYDNVIS AQHAIQFMNG
YFVNNKYLKV QLKKGETVEN TNS
