ID   ARP5L_BOVIN             Reviewed;         153 AA.
AC   Q5E963;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Actin-related protein 2/3 complex subunit 5-like protein;
DE   AltName: Full=Arp2/3 complex 16 kDa subunit 2;
DE            Short=ARC16-2;
GN   Name=ARPC5L;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal cerebellum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function as component of the Arp2/3 complex which is
CC       involved in regulation of actin polymerization and together with an
CC       activating nucleation-promoting factor (NPF) mediates the formation of
CC       branched actin networks. {ECO:0000250}.
CC   -!- SUBUNIT: May be a component of the Arp2/3 complex in which it may
CC       replace ARPC5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell
CC       projection {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ARPC5 family. {ECO:0000305}.
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DR   EMBL; BT021057; AAX09074.1; -; mRNA.
DR   EMBL; BC120185; AAI20186.1; -; mRNA.
DR   RefSeq; NP_001029909.1; NM_001034737.1.
DR   AlphaFoldDB; Q5E963; -.
DR   SMR; Q5E963; -.
DR   STRING; 9913.ENSBTAP00000020318; -.
DR   PaxDb; Q5E963; -.
DR   PeptideAtlas; Q5E963; -.
DR   PRIDE; Q5E963; -.
DR   Ensembl; ENSBTAT00000020318; ENSBTAP00000020318; ENSBTAG00000015278.
DR   GeneID; 613421; -.
DR   KEGG; bta:613421; -.
DR   CTD; 81873; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015278; -.
DR   VGNC; VGNC:26166; ARPC5L.
DR   eggNOG; KOG3380; Eukaryota.
DR   GeneTree; ENSGT00940000158501; -.
DR   HOGENOM; CLU_101888_1_1_1; -.
DR   InParanoid; Q5E963; -.
DR   OMA; SQIQGRN; -.
DR   OrthoDB; 1565115at2759; -.
DR   TreeFam; TF319716; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000015278; Expressed in nasopharynx and 107 other tissues.
DR   GO; GO:0005885; C:Arp2/3 protein complex; IBA:GO_Central.
DR   GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR   GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IBA:GO_Central.
DR   GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR   Gene3D; 1.25.40.190; -; 1.
DR   InterPro; IPR006789; ARPC5.
DR   InterPro; IPR036743; ARPC5_sf.
DR   InterPro; IPR030075; ARPC5L.
DR   PANTHER; PTHR12644; PTHR12644; 1.
DR   PANTHER; PTHR12644:SF2; PTHR12644:SF2; 1.
DR   Pfam; PF04699; P16-Arc; 1.
DR   PIRSF; PIRSF039096; p16-ARC; 1.
DR   SUPFAM; SSF69103; SSF69103; 1.
PE   2: Evidence at transcript level;
KW   Actin-binding; Cell projection; Cytoplasm; Cytoskeleton; Phosphoprotein;
KW   Reference proteome.
FT   CHAIN           1..153
FT                   /note="Actin-related protein 2/3 complex subunit 5-like
FT                   protein"
FT                   /id="PRO_0000279479"
FT   MOD_RES         64
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BPX5"
SQ   SEQUENCE   153 AA;  16941 MW;  A9EF1A85D23007F2 CRC64;
     MARNTLSSRF RRVDIDEFDE NKFVDEQEEA AAAAGEPGPD PSEVDGLLRQ GDMLRAFHAA
     LRNSPVNTKN QAVKERAQGV VLKVLTNFKS SEIEQAVQSL DRNGIDLLMK YIYKGFEKPT
     ENSSAVLLQW HEKALAVGGL GSIIRVLTAR KTV