ID   ARP5_AEDAE              Reviewed;         655 AA.
AC   Q17GZ9;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Actin-related protein 5;
GN   Name=Arp5 {ECO:0000250|UniProtKB:Q9VEC3}; ORFNames=AAEL002822;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1] {ECO:0000312|EMBL:EAT45925.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- FUNCTION: Proposed core component of the chromatin remodeling Ino80
CC       complex which is involved in transcriptional regulation, DNA
CC       replication and probably DNA repair. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the chromatin remodeling Ino80 complex.
CC       {ECO:0000250|UniProtKB:Q9VEC3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9VEC3}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP5 subfamily. {ECO:0000305}.
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DR   EMBL; CH477254; EAT45925.1; -; Genomic_DNA.
DR   RefSeq; XP_001656005.1; XM_001655955.1.
DR   AlphaFoldDB; Q17GZ9; -.
DR   STRING; 7159.AAEL002822-PA; -.
DR   GeneID; 5576227; -.
DR   KEGG; aag:5576227; -.
DR   VEuPathDB; VectorBase:AAEL002822; -.
DR   eggNOG; KOG0681; Eukaryota.
DR   HOGENOM; CLU_008246_1_0_1; -.
DR   InParanoid; Q17GZ9; -.
DR   OMA; TNWNHQE; -.
DR   OrthoDB; 344271at2759; -.
DR   PhylomeDB; Q17GZ9; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006338; P:chromatin remodeling; ISS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR027664; Arp5.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   PANTHER; PTHR11937:SF16; PTHR11937:SF16; 1.
DR   Pfam; PF00022; Actin; 1.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Coiled coil; DNA damage; DNA recombination; DNA repair; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..655
FT                   /note="Actin-related protein 5"
FT                   /id="PRO_0000307116"
FT   REGION          368..387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          287..314
FT                   /evidence="ECO:0000255"
FT   COILED          346..377
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        368..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   655 AA;  74905 MW;  4AD4387121F2C821 CRC64;
     MSLFDIEDIK VKPDIVCTYP DPTVPPDAAI VIDNGSYHCR AGWAGKDVPS LVFKNVLAKP
     RKDRSKKDTS EVVVPTVQIG NDITNIEAVR FQLRTQFDRN VVTHLHVQEQ IFDYLFGRLG
     INADGCVPHP VLLTECVANP NYSRMLMSEL MFECYGIPGI VYAVDGLLSY RMNGGQDSGL
     IVSCGYQATH VIPVLNGRMV EDKVRRINLG GFNMINFMFR LLQLKYPVHV NAITLSRAET
     MIHNYCSFAY DYTESLRNWA LLEFYEQNVI KIQLPYNQNV SAPTLTAEQR LEKRKELSRR
     LAEINLRKRE EKLAEDKVLL TRMLAAEDTL DDEDNVGFTL HEFSVKNVDE YRKMIVTLRE
     RIAKTTQKMN SQQTNNQPEE KPLQLLQPPP NMTIEEWVIE TRRKRDEILD KKQIRKQRKQ
     DLAKRRTAAA QERMRIISHL AKKEKGVDDF GMRDEDWDVY KSISREGDSD SDAENEKLIE
     CEEILKQHDS TFVEPVVAPG NIAEFHQLHI GVERIRVPEI LFQPSMIGVQ EAGLTGTIDY
     VLKLFPKEDQ VKLVGNVMLT GGCANIRGFK ERLSRELQAI LPFQSVYNLM VAGSPSLDAW
     RGASQFANSQ EFKQSLITRQ LYDECGGEYF KEHTASNFYY PTPSQVSSAL NDTFN