ID   NUP82_SCHPO             Reviewed;         803 AA.
AC   Q9P382;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Nucleoporin nup82 {ECO:0000312|EMBL:CAB99395.1};
DE   AltName: Full=Nuclear pore protein nup82 {ECO:0000250|UniProtKB:P40368};
GN   Name=nup82 {ECO:0000250|UniProtKB:P40368}; ORFNames=SPBC13A2.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1] {ECO:0000312|EMBL:CAB99395.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2] {ECO:0000305}
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC       NPC components, collectively referred to as nucleoporins (NUPs), can
CC       play the role of both NPC structural components and of docking or
CC       interaction partners for transiently associated nuclear transport
CC       factors (By similarity). {ECO:0000250|UniProtKB:P40368}.
CC   -!- SUBUNIT: Component of the nuclear pore complex (NPC) (By similarity).
CC       NPC constitutes the exclusive means of nucleocytoplasmic transport.
CC       NPCs allow the passive diffusion of ions and small molecules and the
CC       active, nuclear transport receptor-mediated bidirectional transport of
CC       macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and
CC       ribosomal subunits across the nuclear envelope (By similarity).
CC       {ECO:0000250|UniProtKB:P40368}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC       {ECO:0000269|PubMed:16823372}. Nucleus membrane
CC       {ECO:0000305|PubMed:16823372}; Peripheral membrane protein
CC       {ECO:0000305|PubMed:16823372}; Cytoplasmic side
CC       {ECO:0000305|PubMed:16823372}.
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DR   EMBL; CU329671; CAB99395.1; -; Genomic_DNA.
DR   RefSeq; NP_596415.1; NM_001022334.2.
DR   AlphaFoldDB; Q9P382; -.
DR   SMR; Q9P382; -.
DR   BioGRID; 276250; 1.
DR   STRING; 4896.SPBC13A2.02.1; -.
DR   iPTMnet; Q9P382; -.
DR   MaxQB; Q9P382; -.
DR   PaxDb; Q9P382; -.
DR   PRIDE; Q9P382; -.
DR   DNASU; 2539697; -.
DR   EnsemblFungi; SPBC13A2.02.1; SPBC13A2.02.1:pep; SPBC13A2.02.
DR   GeneID; 2539697; -.
DR   KEGG; spo:SPBC13A2.02; -.
DR   PomBase; SPBC13A2.02; nup82.
DR   VEuPathDB; FungiDB:SPBC13A2.02; -.
DR   eggNOG; ENOG502QUNM; Eukaryota.
DR   HOGENOM; CLU_006117_0_0_1; -.
DR   InParanoid; Q9P382; -.
DR   OMA; WHPLGVN; -.
DR   PhylomeDB; Q9P382; -.
DR   Reactome; R-SPO-159227; Transport of the SLBP independent Mature mRNA.
DR   Reactome; R-SPO-159231; Transport of Mature mRNA Derived from an Intronless Transcript.
DR   Reactome; R-SPO-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR   Reactome; R-SPO-3232142; SUMOylation of ubiquitinylation proteins.
DR   Reactome; R-SPO-4085377; SUMOylation of SUMOylation proteins.
DR   Reactome; R-SPO-4551638; SUMOylation of chromatin organization proteins.
DR   Reactome; R-SPO-4570464; SUMOylation of RNA binding proteins.
DR   Reactome; R-SPO-5578749; Transcriptional regulation by small RNAs.
DR   PRO; PR:Q9P382; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005635; C:nuclear envelope; HDA:PomBase.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005643; C:nuclear pore; IDA:PomBase.
DR   GO; GO:0044614; C:nuclear pore cytoplasmic filaments; ISO:PomBase.
DR   GO; GO:0044612; C:nuclear pore linkers; ISO:PomBase.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR   GO; GO:0006406; P:mRNA export from nucleus; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR   GO; GO:0000056; P:ribosomal small subunit export from nucleus; IBA:GO_Central.
DR   InterPro; IPR037700; NUP88/NUP82.
DR   PANTHER; PTHR13257; PTHR13257; 1.
PE   3: Inferred from homology;
KW   Membrane; mRNA transport; Nuclear pore complex; Nucleus; Protein transport;
KW   Reference proteome; Translocation; Transport.
FT   CHAIN           1..803
FT                   /note="Nucleoporin nup82"
FT                   /id="PRO_0000351141"
SQ   SEQUENCE   803 AA;  90612 MW;  BF22FC063FD7C512 CRC64;
     MASTIMSQEV SWTDILEKHP ALRWIKPIPE DWEIFPKHLC AFESFLYVAV GQEVRSLDCR
     LLKHKNEASH KNFYKKLFNP ELDFMIEQIC LSKNGRFLAV VGKSKIVILG LRSKLSEQNP
     LAESVSNFGE SVNNFSNSEH QENGTNSLKL SEVTICSVAV INPSSQIVSV RFHPLGKSGR
     SLVVLTETSL LLYEAGNGVL MPDYEIPLKL THQASNSFDA DVDLHIPTAF CFSNVSQGWG
     VFTIYILTRG GDVFSVCPVM PANAMIPQDV LKQIRLILTK KEDDADAENH RRNVHWITKL
     LGEAALANDL STSFVISEGS SELFDSSDYV SVRRPDDFSF IPSMQGPFLL QPAVADDELI
     EDYCDIYSFG MNPIDVLAIG GSEGRLDLLL LVSEVSGRWS KLNDHGLASM KLIVSQVHSL
     YLSNNNPYMV LQPDIQSPYS LIAYHANGLH VVDIESWARD LNLNFENSEF LNNEEENDED
     ELSNVLVSIP SRTSVLERLD TNPLNESTDA VVGCAQLYYP SLGKILISLT RNWQTTVFDD
     SDLATMGVNK ESLSNEMDYS KSLGTSSLEQ VDDLDEKLTY TPLYVSLLEK TPFTDPSIPS
     LVERTIVPAE LQNEITVSSA SLRFLGKVVA RYRETLNLLD HGCSELHHRL KLQREEYERQ
     QNHIYKLSDR ISNFREKAWS TEHLEHLTSD MSMCEKRIDQ VLQRVMDLRV PDLSDKEKQF
     IKEIGNYKEK VTGERGIEKR VETLKTLLQR TKPRDAQTTL VASSSDMRLA AIEQLQKLLA
     QQSLSIKELK TKTVSFQRLL QTS